N6-(2-Phenylethyl)adenosine

Modify Date: 2024-01-02 16:13:30

N6-(2-Phenylethyl)adenosine Structure
N6-(2-Phenylethyl)adenosine structure
Common Name N6-(2-Phenylethyl)adenosine
CAS Number 20125-39-7 Molecular Weight 371.39000
Density 1.57g/cm3 Boiling Point 723.5ºC at 760 mmHg
Molecular Formula C18H21N5O4 Melting Point N/A
MSDS Chinese USA Flash Point 391.3ºC

 Use of N6-(2-Phenylethyl)adenosine


N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist.

 Names

Name N6-(2-Phenylethyl)adenosine
Synonym More Synonyms

 N6-(2-Phenylethyl)adenosine Biological Activity

Description N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist.
Related Catalog

 Chemical & Physical Properties

Density 1.57g/cm3
Boiling Point 723.5ºC at 760 mmHg
Molecular Formula C18H21N5O4
Molecular Weight 371.39000
Flash Point 391.3ºC
Exact Mass 371.15900
PSA 125.55000
LogP 0.16540
Vapour Pressure 5.72E-22mmHg at 25°C
Index of Refraction 1.741

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synthetic Route

~94%

N6-(2-Phenylethyl)adenosine Structure

N6-(2-Phenyleth...

CAS#:20125-39-7

Literature: METHYLGENE INC. Patent: US2008/132525 A1, 2008 ; Location in patent: Page/Page column 13 ;

~92%

N6-(2-Phenylethyl)adenosine Structure

N6-(2-Phenyleth...

CAS#:20125-39-7

Literature: Nishikawa, Shiro; Kumazawa, Zenzaburo; Kashimura, Naoki; Nishimiki, Yoshio; Uemura, Shoji Agricultural and Biological Chemistry, 1986 , vol. 50, # 9 p. 2243 - 2250

~%

N6-(2-Phenylethyl)adenosine Structure

N6-(2-Phenyleth...

CAS#:20125-39-7

Literature: Schering Aktiengesellschaft Patent: US3983104 A1, 1976 ;

~%

N6-(2-Phenylethyl)adenosine Structure

N6-(2-Phenyleth...

CAS#:20125-39-7

Literature: Schering Aktiengesellschaft Patent: US3983104 A1, 1976 ;

 Articles5

More Articles
Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin.

Nucleic Acids Res. 39 , 4373-86, (2011)

The carbon catabolite repressor protein 4 (Ccr4)-Negative on TATA (Not) complex controls gene expression at two levels. In the nucleus, it regulates the basal transcription machinery, nuclear receptor...

Exploring distal regions of the A3 adenosine receptor binding site: sterically constrained N6-(2-phenylethyl)adenosine derivatives as potent ligands.

Bioorg. Med. Chem. 12 , 2021-2034, (2004)

We synthesized phenyl ring-substituted analogues of N(6)-(1S,2R)-(2-phenyl-1-cyclopropyl)adenosine, which is highly potent in binding to the human A(3)AR with a Ki value of 0.63 nM. The effects of the...

Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice.

Eur. J. Pharmacol. 371 , 137-145, (1999)

We have studied the effects of selective and non-selective adenosine receptor agonists and antagonists in audiogenic-seizure-sensitive DBA/2 mice, an animal model of generalized reflex epilepsy. With ...

 Synonyms

2-(hydroxymethyl)-5-[6-(2-phenylethylamino)purin-9-yl]oxolane-3,4-diol
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