Z-Leu-OH
Suppliers
Names
[ CAS No. ]:
2018-66-8
[ Name ]:
Z-Leu-OH
[Synonym ]:
N-[(Benzyloxy)carbonyl]-L-leucine
N-(Benzyloxycarbonyl)-L-leucine (N-(Benzyloxycarbonyl)leucine
Z-L-Leucine
EINECS 217-960-3
N-Carbobenzyloxy-L-leucine
(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid
N-Benzyloxycarbonyl-L-leucine
Cbz-L-Leu-OH
Carbobenzoxyleucine
Benzyloxycarbonylleucine
dl-Leucine, N-[(phenylmethoxy)carbonyl]-
N-(Benzyloxycarbonyl)-L-leucine N-(B
(S)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acid
Z-Leu-OH
N-Benzyloxycarbonylleucine
L-Leucine, N-[(phenylmethoxy)carbonyl]-
N-Cbz-L-leucine
N-[(Benzyloxy)carbonyl]leucine
MFCD00026494
Cbz-L-leucine
Leucine, N-[(phenylmethoxy)carbonyl]-
Benzyloxycarbonyl-L-leucine
N-Carbobenzoxy-L-leucine
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
442.8±38.0 °C at 760 mmHg
[ Molecular Formula ]:
C14H19NO4
[ Molecular Weight ]:
265.305
[ Flash Point ]:
221.6±26.8 °C
[ Exact Mass ]:
265.131409
[ PSA ]:
75.63000
[ LogP ]:
3.12
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.528
[ Storage condition ]:
2~8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OH2921000
- CHEMICAL NAME :
- Leucine, N-carboxy-, N-benzyl ester, L-
- CAS REGISTRY NUMBER :
- 2018-66-8
- BEILSTEIN REFERENCE NO. :
- 1253861
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C14-H19-N-O4
- MOLECULAR WEIGHT :
- 265.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravaginal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 280 mg/kg
- SEX/DURATION :
- female 28 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979
Safety Information
[ Symbol ]:
GHS02, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H351-H361d
[ Precautionary Statements ]:
P281
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R10;R20/22;R37/38;R40;R41
[ Safety Phrases ]:
S16-S26-S36/37/39-S45
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
OH2921000
[ HS Code ]:
2924299090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%