3-Chloro-4-[(3-fluorobenzyl)oxy]aniline

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Names

[ CAS No. ]:
202197-26-0

[ Name ]:
3-Chloro-4-[(3-fluorobenzyl)oxy]aniline

[Synonym ]:
3-chloro-4-(3-fluoro-benzyloxy)-phenylamine
3-chloro-4-{[(3-fluorophenyl)methyl]oxy}aniline
ZR CG DO1R CF
3-Chloro-4-(3-fluorobenzyloxy)aniline
3-Chloro-4-[(3-fluorobenzyl)oxy]aniline
3-chloro-4-((3-fluorobenzyl)oxy)aniline
4-(3-fluorobenzyloxy)-3-chlorobenzenamine
3-Chloro-4-[(3-fluorophenyl)methoxy]benzenamine
Benzenamine, 3-chloro-4-[(3-fluorophenyl)methoxy]-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
387.9±32.0 °C at 760 mmHg

[ Melting Point ]:
78.0 to 82.0 °C

[ Molecular Formula ]:
C13H11ClFNO

[ Molecular Weight ]:
251.684

[ Flash Point ]:
188.4±25.1 °C

[ Exact Mass ]:
251.051315

[ PSA ]:
35.25000

[ LogP ]:
3.28

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.607

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
3077

[ Packaging Group ]:
III

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloro-4-nitrophenyl 3-fluorobenzyl ether
  • 2-chloro-1-(3-fluoro-benzoyloxy)-4-nitro-benzene
  • 2-Chloro-4-nitrophenol
  • 1-(Bromomethyl)-3-fluorobenzene
  • 3-Chloro-4-fluoronitrobenzene
  • 3-Fluorobenzyl alcohol

DownStream

  • Lapatinib ditosylate hydrate
  • AST-1306
  • AST-1306 (TsOH)
  • 5-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-carbaldehyde
  • N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine
  • Lapatinib (GW572016)
  • HKI 357
  • GW583340 DIHYDROCHLORIDE

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine
  • 5-(4-((3-CHLORO-4-((3-FLUOROBENZYL)OXY)PHENYL)AMINO)QUINAZOLIN-6-YL)FURAN-2-CARBALDEHYDE HYDROCHLORIDE
  • 6-bromo-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)thieno[3,2-d]pyrimidin-4-amine
  • 6-bromo-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)thieno[2,3-d]pyrimidin-4-amine
  • 3-Chloro-4-[(2-fluorobenzyl)oxy]aniline
  • 3-Chloro-4-fluoro-N-(3-fluorobenzyl)aniline
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-(2-Bromo-6-fluorophenyl)-3-methylbutanoic acid
  • 3-[2-(Hydroxymethyl)bicyclo[2.2.2]octan-2-yl]azetidin-3-ol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 9-(4-Chloro-6-(dibenzo[b,d]furan-1-yl)-1,3,5-triazin-2-yl)-9H-carbazole
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde