etoricoxib

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Names

[ CAS No. ]:
202409-33-4

[ Name ]:
etoricoxib

[Synonym ]:
Nucoxia
UNII-WRX4NFY03R
5-chloro-3(methylsulfonyl)phenyl-2-((4-methyl)-3-pyridyl)-pyridine
5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine
Tauxib
Algix
5-chloro-3-(4-(methylsulfonyl)phenyl)-2-(2-methyl-5-pyridinyl)pyridine
5-chloro-3-(4-(methylsulfonyl)phenyl)-2-(Methyl-5-pyridinyl) pyridine
5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
etoricoxib
Arcoxia
Etoricoxibe
2-(6-methylpyrid-3-yl)-3-(4-methylsulfonylphenyl)-5-chloropyridine
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
[14C]-Etoricoxib
3-(4-methylsulfonylphenyl)-2-(2-methyl-5-pyridyl)-5-chloro-pyridine
MK-0663
2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
MK-663
MFCD06797512

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
510.0±50.0 °C at 760 mmHg

[ Melting Point ]:
134-135°C

[ Molecular Formula ]:
C18H15ClN2O2S

[ Molecular Weight ]:
358.842

[ Flash Point ]:
262.2±30.1 °C

[ Exact Mass ]:
358.054260

[ PSA ]:
68.30000

[ LogP ]:
2.21

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.601

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H310

[ Precautionary Statements ]:
P280-P302 + P350-P310

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 2811 6.1 / PGII

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Precursor & DownStream

Precursor

  • 5-Chloro-6'-methyl-3-(4-(methylthio)phenyl)-2,3'-bipyridine(EtoricoxibImpurity)
  • 3-amino-2-chloroacrolein
  • 1-(6-Methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone
  • trimethyl-(6-methylpyridin-3-yl)stannane
  • 2,5-dichloro-3-(4-methylsulfonyl)phenyl-pyridine
  • 1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone
  • Methyl 6-methylnicotinate
  • N-METHOXY-6,N-DIMETHYL-NICOTINAMIDE
  • 2-Amino-5-chloropyridine
  • 3-bromo-5-chloropyridin-2-amine

DownStream

  • Etoricoxib N1'-Oxide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Analgesic activity of Eugenia jambolana leave constituent: a dikaempferol rhamnopyranoside from ethyl acetate soluble fraction.

Pharm. Biol. 52(8) , 1069-78, (2014)

Eugenia jambolana Lam. (Myrtaceae) is a medicinal plant used in folk medicine for the treatment of diabetes, inflammation, and pain.We investigated the antinociceptive effect of kaempferol-7-O-α-l-rha...

Downregulation of NF-κB and PCNA in the regulatory pathways of apoptosis by cyclooxygenase-2 inhibitors in experimental lung cancer.

Mol. Cell Biochem. 369(1-2) , 75-86, (2012)

Non-steroidal anti-inflammatory drugs (NSAIDs) are emerging as novel chemopreventive agents against a variety of cancers owing to their capability in blocking the tumor development by cellular prolife...

Angiostatic role of the selective cyclooxygenase-2 inhibitor etoricoxib (MK0663) in experimental lung cancer.

Biomed. Pharmacother. 66(6) , 474-83, (2012)

Lung cancer was induced in Sprague-Dawley rats by a single intra-tracheal instillation of 9,10-dimethybenz(a)anthracene (DMBA) and evaluated the anti-angiogenic action of etoricoxib, which is a select...


More Articles

Related Compounds

  • Etoricoxib D4
  • Etoricoxib-d3
  • Etoricoxib-13C,d3
  • Etoricoxib N1'-Oxide
  • Etoricoxib Impurity 2
  • Etoricoxib Impurity 3
  • N1-(3-methoxybenzyl)-N2-((3-(phenylsulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
  • N1-(4-methoxyphenethyl)-N2-((3-(phenylsulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
  • N1-(2-methoxybenzyl)-N2-((3-(phenylsulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
  • N1-((3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-methoxyethyl)oxalamide
  • N1-((3-((4-fluorophenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(3-methoxybenzyl)oxalamide
  • N1-((3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-methylbenzyl)oxalamide
  • N1-((3-(mesitylsulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(3-phenylpropyl)oxalamide
  • N1-((3-(mesitylsulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(4-methoxybenzyl)oxalamide
  • N1-((3-(mesitylsulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(3-methoxybenzyl)oxalamide
  • N1-((3-(mesitylsulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-methoxybenzyl)oxalamide
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