Ro 04-6790

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Names

[ CAS No. ]:
202466-68-0

[ Name ]:
Ro 04-6790

[Synonym ]:
4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide
4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide dihydrobromide
Benzenesulfonamide, 4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-
4-Amino-N-[2,6-bis(methylamino)pyrimidin-4-yl]benzenesulfonamide
Ro 04-6790
4-amino-N-(2,6-bis-methylaminopyrimidin-4-yl)benzenesulfonamide

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
595.8±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₆N₆O₂S

[ Molecular Weight ]:
308.359

[ Flash Point ]:
314.1±32.9 °C

[ Exact Mass ]:
308.105530

[ PSA ]:
130.41000

[ LogP ]:
-0.52

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.700

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DA9462500

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors.

Br. J. Pharmacol. 124 , 556-562, (1998)

1. This study describes the in vitro characterization of two potent and selective 5-HT6 receptor antagonists at the rat and human recombinant 5-HT6 receptor. 2. In binding assays with [3H]-LSD, 4-amin...

Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats.

Br. J. Pharmacol. 126 , 1537-1542, (1999)

1. The present study examined the effects of the selective 5-HT6 receptor antagonist 4-amino-N-(2, 6 bis-methylamino-pyrimidin-4-yl)-benzene sulphonamide (Ro 04-6790) on locomotor activity and uncondi...

Ro 04-6790
Ro 04-5595 hydrochloride
Tetradecyltrimethylammonium bromide
1-[2-(4-chlorophenyl)ethyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol,hydrochloride
1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one,2-ethoxybenzamide,1,3,7-trimethylpurine-2,6-dione
Ro 41-7812
benzyl N-[2-(4-bromophenyl)propyl]carbamate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1-[(Piperazin-1-yl)methyl]cyclopentan-1-ol
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
1-(3-Fluoropyridin-2-yl)cyclobutan-1-amine
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde