Ro 04-6790

Ro 04-6790 Structure
Ro 04-6790 structure
Common Name Ro 04-6790
CAS Number 202466-68-0 Molecular Weight 308.359
Density 1.5±0.1 g/cm3 Boiling Point 595.8±60.0 °C at 760 mmHg
Molecular Formula C12H16N6O2S Melting Point N/A
MSDS USA Flash Point 314.1±32.9 °C

Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors.

Br. J. Pharmacol. 124 , 556-562, (1998)

1. This study describes the in vitro characterization of two potent and selective 5-HT6 receptor antagonists at the rat and human recombinant 5-HT6 receptor. 2. In binding assays with [3H]-LSD, 4-amino-N-(2,6 bis-methylamino-pyrimidin-4-yl)-benzene sulphonami...

Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats.

Br. J. Pharmacol. 126 , 1537-1542, (1999)

1. The present study examined the effects of the selective 5-HT6 receptor antagonist 4-amino-N-(2, 6 bis-methylamino-pyrimidin-4-yl)-benzene sulphonamide (Ro 04-6790) on locomotor activity and unconditioned behaviour in male Sprague Dawley rats (230-300 g). 2...