M-6-G TRIFLUOROACETATE-HYDRATE
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Names
Chemical & Physical Properties
[ Density]:
1.64g/cm3
[ Boiling Point ]:
731.6ºC at 760mmHg
[ Melting Point ]:
237-240°C (dec.)
[ Molecular Formula ]:
C23H27NO9
[ Molecular Weight ]:
461.46200
[ Flash Point ]:
396.3ºC
[ Exact Mass ]:
461.16900
[ PSA ]:
149.15000
[ Vapour Pressure ]:
1.8E-22mmHg at 25°C
[ Index of Refraction ]:
1.731
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ6500700
- CHEMICAL NAME :
- Glucopyranosiduronic acid, 7,8-didehydro-4,5-alpha-epoxy-3-hydroxy-17-methylmorp hinan-6- alpha-yl-, beta-D-
- CAS REGISTRY NUMBER :
- 20290-10-2
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C23-H27-N-O9
- MOLECULAR WEIGHT :
- 461.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 432 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67(4),97P,1971
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H317-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
20/21/22-43
[ Safety Phrases ]:
36
[ RIDADR ]:
UN 1993C 3 / PGIII
[ WGK Germany ]:
3
[ RTECS ]:
LZ6500700
Articles
Life Sci. 109(2) , 104-10, (2014)
Morphine is extensively metabolized to neurotoxic morphine-3-glucuronide (M3G) and opioid agonist morphine-6-glucuronide (M6G). Due to these different roles, interindividual variability and co-adminis...
Rev. Med. Liege. 68(5-6) , 298-302, (2013)
Rapid Opiate Detoxification under Anesthesia (RODA) involves the use of opiate antagonists combined with anesthesia and pharmacotherapy to reduce withdrawal symptoms. The aim of our study was to measu...
Yakugaku Zasshi 131(10) , 1445-51, (2011)
Opioid analgesics exhibit cationic properties under physiological conditions, and the mechanism underlying permeation of the blood-brain barrier thus cannot be fully explained by simple diffusion alon...