N-BOC-cis-4-fluoro-L-proline

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Names

[ CAS No. ]:
203866-13-1

[ Name ]:
N-BOC-cis-4-fluoro-L-proline

[Synonym ]:
Boc-cis-4F-Pro
(2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S,4S)-
BOC-FLP-OH
(2S,4S)-N-Boc-4-fluoroproline
BOC-CIS-PRO(4-F)-OH
(2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid
N-Boc-cis-4-fluoro-L-proline
BOC-CIS-4-FLUORO-PRO-OH
(4S)-1-(tert-Butoxycarbonyl)-4-fluor-L-prolin
(2S,4S)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid
(4S)-1-(tert-Butoxycarbonyl)-4-fluoro-L-proline
(4S)-4-Fluoro-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
1-(tert-butoxycarbonyl)-(4S)-fluoropyrrolidine-(2S)-carboxylic acid
N-t-BOC-cis-4-Fluoro-L-proline
BOC-CIS-4-FLUORO-L-PROLINE
N-(tert-Butoxycarbonyl)-cis-4-fluoro-L-proline
MFCD04973957
N-tert-butoxycarbonyl-cis-4-fluoro-L-proline
1-(tert-butoxycarbonyl)-(4S)-fluoro-(2S)-pyrrolidinylcarboxylic

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
346.0±42.0 °C at 760 mmHg

[ Melting Point ]:
157-161.ºC

[ Molecular Formula ]:
C10H16FNO4

[ Molecular Weight ]:
233.24

[ Flash Point ]:
163.0±27.9 °C

[ Exact Mass ]:
233.106339

[ PSA ]:
66.84000

[ LogP ]:
0.48

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.488

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-t-BOC-trans-4-Fluoro-L-proline methyl ester
  • N-tert-butoxycarbonyl-(2S,4S)-4-fluoroproline benzyl ester
  • boc-hyp-obzl
  • Boc-Hyp-OMe
  • Di-tert-butyl dicarbonate
  • H-Hyp-OMe hydrochloride
  • methyl n-boc-l-proline-3-ene
  • METHYL N-BOC-L-PROLINE-4-ENE

DownStream

  • (2S,4S)-1-Boc-2-cyano-4-fluoropyrrolidine
  • Fmoc-cis-4-fluoro-Pro-OH

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-Boc-cis-4-Fluoro-L-proline methyl ester
  • tert-butyl(2S,4S)-4-fluoro-2-formylpyrrolidine-1-carboxylate
  • N-BOC-cis-4-Hydroxy-L-proline
  • N-Boc-cis-4-azido-L-proline (dicyclohexylammonium) salt
  • N-Boc-cis-4-iodo-L-proline methyl ester
  • N-Boc-cis-4-phenoxy-L-proline benzyl ester