N-BOC-cis-4-fluoro-L-proline

Modify Date: 2024-01-10 19:17:40

N-BOC-cis-4-fluoro-L-proline Structure
N-BOC-cis-4-fluoro-L-proline structure
 Common Name N-BOC-cis-4-fluoro-L-proline
CAS Number 203866-13-1 Molecular Weight 233.24
Density 1.3±0.1 g/cm3 Boiling Point 346.0±42.0 °C at 760 mmHg
Molecular Formula C10H16FNO4 Melting Point 157-161.ºC
MSDS Chinese USA Flash Point 163.0±27.9 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of N-BOC-cis-4-fluoro-L-proline


N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name (2S,4S)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
Synonym More Synonyms

 N-BOC-cis-4-fluoro-L-proline Biological Activity

Description N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 346.0±42.0 °C at 760 mmHg
Melting Point 157-161.ºC
Molecular Formula C10H16FNO4
Molecular Weight 233.24
Flash Point 163.0±27.9 °C
Exact Mass 233.106339
PSA 66.84000
LogP 0.48
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.488
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

N-t-BOC-trans-4-Fluoro-L-proline methyl ester structure

N-t-BOC-trans-4...

CAS#:203866-16-4

~98%

N-BOC-cis-4-fluoro-L-proline Structure

N-BOC-cis-4-flu...

CAS#:203866-13-1

Literature: SUNSHINE LAKE PHARMA CO.,LTD.; ZHANG, Jiancun; ZHANG, Yingjun; XIE, Hongming; REN, Qingyun; HU, Bailin; FU, Changping; WU, Xiwei; LI, Shifeng; WANG, Chenglin; ZHANG, Zhikeng Patent: WO2014/82379 A1, 2014 ; Location in patent: Page/Page column 144; 145 ;
N-tert-butoxycarbonyl-(2S,4S)-4-fluoroproline benzyl ester structure

N-tert-butoxyca...

CAS#:587888-04-8

~%

N-BOC-cis-4-fluoro-L-proline Structure

N-BOC-cis-4-flu...

CAS#:203866-13-1

Literature: Journal of the American Chemical Society, , vol. 125, # 31 p. 9262 - 9263
boc-hyp-obzl structure

boc-hyp-obzl

CAS#:89813-47-8

~%

N-BOC-cis-4-fluoro-L-proline Structure

N-BOC-cis-4-flu...

CAS#:203866-13-1

Literature: Journal of the American Chemical Society, , vol. 125, # 31 p. 9262 - 9263
Boc-Hyp-OMe structure

Boc-Hyp-OMe

CAS#:74844-91-0

~%

N-BOC-cis-4-fluoro-L-proline Structure

N-BOC-cis-4-flu...

CAS#:203866-13-1

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4167 - 4172
Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

~%

N-BOC-cis-4-fluoro-L-proline Structure

N-BOC-cis-4-flu...

CAS#:203866-13-1

Literature: Tetrahedron Letters, , vol. 39, # 10 p. 1169 - 1172
H-Hyp-OMe hydrochloride structure

H-Hyp-OMe hydro...

CAS#:40216-83-9

~%

N-BOC-cis-4-fluoro-L-proline Structure

N-BOC-cis-4-flu...

CAS#:203866-13-1

Literature: Tetrahedron Letters, , vol. 39, # 10 p. 1169 - 1172
methyl n-boc-l-proline-3-ene structure

methyl n-boc-l-...

CAS#:74844-93-2

METHYL N-BOC-L-PROLINE-4-ENE structure

METHYL N-BOC-L-...

CAS#:83548-46-3

N-t-BOC-trans-4-Fluoro-L-proline methyl ester structure

N-t-BOC-trans-4...

CAS#:203866-16-4

~0%

(S)-1-Boc-2,3-dihydro-1H-pyrrole-2-carboxylic acid structure

(S)-1-Boc-2,3-d...

CAS#:90104-21-5

Detail
Literature: WO2006/80401 A1, ; Page/Page column 38-40 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Boc-cis-4F-Pro
(2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S,4S)-
BOC-FLP-OH
(2S,4S)-N-Boc-4-fluoroproline
BOC-CIS-PRO(4-F)-OH
(2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid
N-Boc-cis-4-fluoro-L-proline
BOC-CIS-4-FLUORO-PRO-OH
(4S)-1-(tert-Butoxycarbonyl)-4-fluor-L-prolin
(2S,4S)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid
(4S)-1-(tert-Butoxycarbonyl)-4-fluoro-L-proline
(4S)-4-Fluoro-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
1-(tert-butoxycarbonyl)-(4S)-fluoropyrrolidine-(2S)-carboxylic acid
N-t-BOC-cis-4-Fluoro-L-proline
BOC-CIS-4-FLUORO-L-PROLINE
N-(tert-Butoxycarbonyl)-cis-4-fluoro-L-proline
MFCD04973957
N-tert-butoxycarbonyl-cis-4-fluoro-L-proline
1-(tert-butoxycarbonyl)-(4S)-fluoro-(2S)-pyrrolidinylcarboxylic
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