1-methylisatin
Suppliers
Names
[ CAS No. ]:
2058-74-4
[ Name ]:
1-methylisatin
[Synonym ]:
INDOLE-2,3-DIONE,1-METHYL
1-Methyl-indole-2,3-dione
1-Methyl-1H-indole-2,3-dione
1H-Indole-2,3-dione, 1-methyl-
N-methylindol-2,3-dione
1-Methylindole-2,3-dione
N-methylisatin
1-methylindoline-2,3-dione
OL-57
EINECS 218-164-9
1-methylisatin
1-Methyl-2,3-indolinedione
N-methylindole-2,3-dione
MFCD00005812
1-methylindole-2,3(1H)-dione
N-Methylindoline-2,3-dione
1H-Indole-2,3-dione,1-methyl
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
294.3±23.0 °C at 760 mmHg
[ Melting Point ]:
130-133 °C(lit.)
[ Molecular Formula ]:
C9H7NO2
[ Molecular Weight ]:
161.157
[ Flash Point ]:
137.4±15.0 °C
[ Exact Mass ]:
161.047684
[ PSA ]:
37.38000
[ LogP ]:
0.58
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.607
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL7939000
- CHEMICAL NAME :
- Indole-2,3-dione, 1-methyl-
- CAS REGISTRY NUMBER :
- 2058-74-4
- BEILSTEIN REFERENCE NO. :
- 0128280
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H7-N-O2
- MOLECULAR WEIGHT :
- 161.17
- WISWESSER LINE NOTATION :
- T56 BNVVJ B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 685 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,858,1981
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H315-H318-H335
[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
R25
[ Safety Phrases ]:
S26-S39-S45
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
NL7939000
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Phys. Chem. B 113(45) , 14904-13, (2009)
In this report, steady state and time-resolved fluorescence along with circular dichroism (CD) spectroscopic, FTIR, and anisotropy investigations were made to reveal the nature of the interactions bet...
Drug Des. Discov. 11(3) , 223-30, (1994)
Alkaline hydrolysis of the title isatin 4 in unbuffered solution obeys a rate law such that kobs varies; is directly proportional to [OH-]2 at pH 10 changes smoothly to kobs varies; is directly propor...
Org. Lett. 9(9) , 1745-8, (2007)
[reaction: see text] The in situ preparation of a sulfonium ylide reagent achieved the highly diastereoselective epoxidation of isatins, so that a new and straightforward access to biologically signif...