1-methylisatin
1-methylisatin structure
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Common Name | 1-methylisatin | ||
|---|---|---|---|---|
| CAS Number | 2058-74-4 | Molecular Weight | 161.157 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 294.3±23.0 °C at 760 mmHg | |
| Molecular Formula | C9H7NO2 | Melting Point | 130-133 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 137.4±15.0 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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Fluorescence spectroscopic characterization of the interaction of human adult hemoglobin and two isatins, 1-methylisatin and 1-phenylisatin: a comparative study.
J. Phys. Chem. B 113(45) , 14904-13, (2009) In this report, steady state and time-resolved fluorescence along with circular dichroism (CD) spectroscopic, FTIR, and anisotropy investigations were made to reveal the nature of the interactions between human adult hemoglobin (Hb) and the isatins, 1-methyli... |
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The hydrolysis of N-methylisatin: on how a simple rate-pH profile may mislead.
Drug Des. Discov. 11(3) , 223-30, (1994) Alkaline hydrolysis of the title isatin 4 in unbuffered solution obeys a rate law such that kobs varies; is directly proportional to [OH-]2 at pH 10 changes smoothly to kobs varies; is directly proportional to [OG-] by pH 13. As in the case of other isatins, ... |
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Straightforward stereoselective synthesis of spiro-epoxyoxindoles.
Org. Lett. 9(9) , 1745-8, (2007) [reaction: see text] The in situ preparation of a sulfonium ylide reagent achieved the highly diastereoselective epoxidation of isatins, so that a new and straightforward access to biologically significant spiro-epoxyoxindoles is provided. The first investiga... |
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Complexes of 2-thiophenecarbonyl and isonicotinoyl hydrazones of 3-(N-methyl)isatin. A study of their antimicrobial activity.
J. Inorg. Biochem. 101(1) , 138-47, (2007) Cobalt(II), nickel(II), copper(II) and zinc(II) complexes of 2-thiophenecarbonyl and isonicotinoyl hydrazones of 3-(N-methyl)isatin (HL(1) and HL(2), respectively) were synthesized and characterized, being the crystal structures of HL(1), HL(2) and [Ni(L(1))(... |
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Combination of N-methylisatin-β-thiosemicarbazone derivative (SCH16) with ribavirin and mycophenolic acid potentiates the antiviral activity of SCH16 against Japanese encephalitis virus in vitro.
Lett. Appl. Microbiol. 55(3) , 234-9, (2012) To investigate the drug to drug interaction of N-methylisatin-β-thiosemicarbazone (MIBT) derivative (SCH16) with ribavirin, mycophenolic acid and pentoxifylline against Japanese encephalitis virus in vitro. Our earlier studies have reported significant antiv... |