N-desmethylchlorpheniramine

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Names

[ CAS No. ]:
20619-12-9

[ Name ]:
N-desmethylchlorpheniramine

[Synonym ]:
Anti-Nlrb1
UNII-0D64JQ680A
Mono-N-desmethyl chlorpheniramine
Chlorphenamine impurity C
Desmethylchlorpheniramine
Anti-Birc1
Desmcp
N-Desmethylchlorpheniramine

Chemical & Physical Properties

[ Density]:
1.118g/cm3

[ Boiling Point ]:
387.7ºC at 760mmHg

[ Molecular Formula ]:
C15H17ClN2

[ Molecular Weight ]:
260.76200

[ Flash Point ]:
188.3ºC

[ Exact Mass ]:
260.10800

[ PSA ]:
24.92000

[ LogP ]:
3.86730

[ Vapour Pressure ]:
3.22E-06mmHg at 25°C

[ Index of Refraction ]:
1.566

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-methylformamide

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Determination of the enantiomers of chlorpheniramine and its main monodesmethyl metabolite in urine using achiral-chiral liquid chromatography.

J. Chromatogr. B. Biomed. Sci. Appl. 707(1-2) , 235-40, (1998)

The enantiomers of chlorpheniramine and its monodesmethyl metabolite were determined separately in urine by using a coupled achiral-chiral chromatographic system. The two enantiomers of the studied co...

Urinary excretion of chlorpheniramine and its metabolites in children.

J. Pharm. Sci. 73(5) , 595-9, (1984)

The pharmacokinetics and urinary excretion of chlorpheniramine were studied in 11 patients, aged 6-16 years, with allergic rhinitis. In these children, chlorpheniramine had a mean elimination half-lif...

Skin permeation of chlorpheniramine maleate and detection of demethylated metabolites by high-performance liquid chromatography.

J. Pharm. Sci. 77(2) , 188-90, (1988)


More Articles

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