N-desmethylchlorpheniramine
N-desmethylchlorpheniramine structure
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Common Name | N-desmethylchlorpheniramine | ||
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| CAS Number | 20619-12-9 | Molecular Weight | 260.76200 | |
| Density | 1.118g/cm3 | Boiling Point | 387.7ºC at 760mmHg | |
| Molecular Formula | C15H17ClN2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 188.3ºC | |
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Determination of the enantiomers of chlorpheniramine and its main monodesmethyl metabolite in urine using achiral-chiral liquid chromatography.
J. Chromatogr. B. Biomed. Sci. Appl. 707(1-2) , 235-40, (1998) The enantiomers of chlorpheniramine and its monodesmethyl metabolite were determined separately in urine by using a coupled achiral-chiral chromatographic system. The two enantiomers of the studied compound and the internal standard were separated from the bi... |
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Urinary excretion of chlorpheniramine and its metabolites in children.
J. Pharm. Sci. 73(5) , 595-9, (1984) The pharmacokinetics and urinary excretion of chlorpheniramine were studied in 11 patients, aged 6-16 years, with allergic rhinitis. In these children, chlorpheniramine had a mean elimination half-life of 13.1 +/- 6.6 h, a mean clearance rate of 7.23 +/- 3.16... |
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Skin permeation of chlorpheniramine maleate and detection of demethylated metabolites by high-performance liquid chromatography.
J. Pharm. Sci. 77(2) , 188-90, (1988)
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