1-(3-chlorophenyl)biguanide hydrochloride

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Names

[ CAS No. ]:
2113-05-5

[ Name ]:
1-(3-chlorophenyl)biguanide hydrochloride

[Synonym ]:
1-(3-Chlorophenyl)biguanide hydrochloride
m-Chlorophenylbiguanide hydrochloride
MFCD00053019
N-m-Chlorophenylbiguanide hydrochloride
m-CPBG hydrochloride

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Boiling Point ]:
434.1ºC at 760mmHg

[ Melting Point ]:
190-194 °C(lit.)

[ Molecular Formula ]:
C8H11Cl2N5

[ Molecular Weight ]:
248.11

[ Flash Point ]:
216.3ºC

[ Exact Mass ]:
247.03900

[ PSA ]:
97.78000

[ LogP ]:
3.33540

[ Appearance of Characters ]:
solid | white

[ Vapour Pressure ]:
9.74E-08mmHg at 25°C

[ Storage condition ]:
Desiccate at RT

[ Water Solubility ]:
H2O: soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU1780000
CHEMICAL NAME :
Biguanide, 1-(m-chlorophenyl)-, monohydrochloride
CAS REGISTRY NUMBER :
2113-05-5
LAST UPDATED :
199007
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H10-Cl-N5.Cl-H
MOLECULAR WEIGHT :
248.14
WISWESSER LINE NOTATION :
MUYZMYUM&MR CG &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
186 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,521,1967
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Endocrine - hyperglycemia
REFERENCE :
IJOCAP Indian Journal of Chemistry. (New Delhi, India) V.1-13, 1963-75. Divided into Indian Journal of Chemistry, Section A and Indian Journal of Chemistry, Section B. Volume(issue)/page/year: 1,218,1962

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DU1780000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Chloroaniline

DownStream

  • N-carbamimidoyl-N'-(3-chloro-phenyl)-urea
  • 3-Chloroaniline

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