2'-Iodoacetophenone

Suppliers

Names

[ Name ]:
2'-Iodoacetophenone

[Synonym ]:
1-(2-iodophenyl)ethan-1-one
2-IC6H4COMe
2′-Iodoacetophenone
MFCD00094998
2-Ac-C6H4-I
2‘-Iodoacetophenone
o-Iodoacetophenone
ortho-iodoacetophenone
2'-Iodoacetophenone
2-Iodoacetophenone
2'-IODO-1,1':3',1''-TERPHENYL
o-acetyl-iodobenzene
1-acetyl-2-iodobenzene
Acetophenone,o-iodo
1-(2-Iodophenyl)ethanone

Chemical & Physical Properties

[ Density]:
1.72 g/mL at 25 °C(lit.)

[ Boiling Point ]:
139-140°C 12mm

[ Molecular Formula ]:
C₈H₇IO

[ Molecular Weight ]:
246.04500

[ Flash Point ]:
218 °F

[ Exact Mass ]:
245.95400

[ PSA ]:
17.07000

[ LogP ]:
2.49380

[ Vapour Pressure ]:
0.00779mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.618(lit.)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2'-Aminoacetophenone
diiodobenzene
Ethanoic anhydride
Acetophenone
(+/-)-1-(2-iodophenyl)-ethanol
1-Chloro-1,3-dihydro-3,3-dimethyl-1,2-benziodoxole
2-Iodobenzaldehyde
METHYLMAGNESIUM IODIDE
2-Iodobenzoyl chloride

DownStream

Benzoic acid,2-acetyl-, methyl ester
2'-Aminoacetophenone
Methyl 4-acetylbenzoate
(R)-α-(Hydroxymethyl)benzeneacetic acid methyl ester
Acetophenone
[N-(trifluoromethanesulfonyl)imino][2-(acetyl)phenyl]-λ3-iodane
4-Bromobenzotrifluoride
3-Methyl-1H-indazole
9-Methylacridine
Ortho-Hydroxyacetophenone

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Trapping evidence for the thermal cyclization of di-(o-acetylphenyl)acetylene to 3,3'-dimethyl-1,1'-biisobenzofuran.

Beilstein J. Org. Chem. 1(1) , 18, (2005)

The reaction of di-(o-acetylphenyl)acetylene (1) with excess dimethyl acetylenedicarboxylate (DMAD) produced bis-DMAD adducts meso-3 and rac-3. This transformation is suggested to involve thermal rear...

Cobalt-catalyzed regioselective carbocyclization reaction of o-iodophenyl ketones and aldehydes with alkynes, acrylates, and acrylonitrile: a facile route to indenols and indenes.

J. Org. Chem. 69(14) , 4781-7, (2004)

An efficient cobalt-catalyzed carbocylization for the synthesis of indenols and indenes and a new method for reductive decyanation are described. 2-Iodophenyl ketones and aldehydes 1a-g undergo carboc...

Cobalt-Catalyzed Carbocyclization of o-Iodobenzaldehydes and o-Iodophenylketones with Alkynes. Chang KJ, et al.

Org. Lett. 5(21) , 3963-3966, (2003)