CX546

Suppliers

Names

[ CAS No. ]:
215923-54-9

[ Name ]:
CX546

[Synonym ]:
CX 546
Lopac-C-271
BDP 17
GR 87
CX546

Chemical & Physical Properties

[ Density]:
1.215g/cm3

[ Boiling Point ]:
422.8ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₇NO₃

[ Molecular Weight ]:
247.29000

[ Flash Point ]:
209.5ºC

[ Exact Mass ]:
247.12100

[ PSA ]:
38.77000

[ LogP ]:
2.02180

[ Vapour Pressure ]:
2.34E-07mmHg at 25°C

[ Index of Refraction ]:
1.573

[ Storage condition ]:
2-8℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex.

Eur. Psychiatry 29(7) , 419-23, (2014)

Ketamine exerts fast acting, robust, and lasting antidepressant effects in a sub-anesthetic dose, however, the underlying mechanisms are still not fully elucidated. Recent studies have suggested that ...

Benzamide-type AMPA receptor modulators form two subfamilies with distinct modes of action.

J. Pharmacol. Exp. Ther. 303 , 1075-1085, (2002)

CX516 (BDP-12) and CX546, two first-generation benzamide-type AMPA receptor modulators, were compared with regard to their influence on AMPA receptor-mediated currents, autaptic responses in cultured ...

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

Proc. Natl. Acad. Sci. U. S. A. 95 , 2597-2602, (1998)

To study regulation in vivo of the promoter for the neural cell adhesion molecule, N-CAM, we have used homologous recombination to insert the bacterial lacZ gene between the transcription and translat...