(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid

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Names

[ CAS No. ]:
220352-36-3

[ Name ]:
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid

[Synonym ]:
trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
(1R,2R)-trans-2-(3,4-difluorophenyl)-1-cyclopropanecarboxylic acid
(1R-trans)-2-(3,4-difluorophenyl)-cyclopropanecarboxylic acid
Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
(1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
308.1±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H8F2O2

[ Molecular Weight ]:
198.166

[ Flash Point ]:
140.1±27.9 °C

[ Exact Mass ]:
198.049240

[ PSA ]:
37.30000

[ LogP ]:
1.74

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.556

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (1R,2R)-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate
  • 3,4-Difluorobenzaldehyde
  • 3,4-Difluorostyrene
  • trans-3,4-Difluorocinnamic acid
  • (2E)-3-(3,4-Difluorophenyl)acryloyl chloride
  • (1S)-2-Chloro-1-(3,4-difluorophenyl)ethanol
  • (2S)-2-(3,4-Difluorophenyl)oxirane
  • 1,2-Difluorobenzene
  • 2-Chloro-1-(3,4-difluorophenyl)ethanone

DownStream

  • Ticagrelor
  • (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
  • (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxamide

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-{[Tert-butyl(dimethyl)silyl]oxy}cycloheptanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide