Cytochalasin C
Suppliers
Names
[ CAS No. ]:
22144-76-9
[ Name ]:
Cytochalasin C
[Synonym ]:
1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-, (7Z,13E)-
Acétate de (7Z,13E)-3-benzyl-6,12-dihydroxy-4,5,10,12-tétraméthyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-décahydro-1H-cycloundéca[d]isoindol-15-yle
EINECS 244-803-6
(7Z,13E)-3-Benzyl-6,12-dihydroxy-4,5,10,12-tetramethyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-decahydro-1H-cycloundeca[d]isoindol-15-ylacetat
(7Z,13E)-3-Benzyl-6,12-dihydroxy-4,5,10,12-tetramethyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-decahydro-1H-cycloundeca[d]isoindol-15-yl acetate
Cytochalasin C from Metarrhizium anisopliae
MFCD00066080
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
714.3±60.0 °C at 760 mmHg
[ Melting Point ]:
260-264ºC
[ Molecular Formula ]:
C30H37NO6
[ Molecular Weight ]:
507.618
[ Flash Point ]:
385.8±32.9 °C
[ Exact Mass ]:
507.262085
[ PSA ]:
112.93000
[ LogP ]:
2.81
[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C
[ Index of Refraction ]:
1.602
[ Storage condition ]:
−20°C
[ Water Solubility ]:
methylene chloride: 5 mg/mL, clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA5300500
- CHEMICAL NAME :
- (11)Cytochalasa-5,13,19-triene-1,17-dione, 21-(acetoxy)-7,18-dihydroxy-16,18-dimethyl- 10-phenyl-, (7S,13E,16S,18R,19E,21R)-
- CAS REGISTRY NUMBER :
- 22144-76-9
- LAST UPDATED :
- 199203
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 21,2268,1973
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H310 + H330-H361
[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+: Very toxic;T: Toxic;
[ Risk Phrases ]:
26/27/28-63
[ Safety Phrases ]:
28-36/37-45
[ RIDADR ]:
UN 1544 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
HA5300500
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
Articles
Biochemistry 19 , 679, (1980)
Twenty cytochalasins were tested for binding to and for inhibition of glucose transport in human erythrocyte membrane. In this membrane three cytochalasin B (CB) binding sites have been identified. Al...
Virchows Arch.,. B, Cell Pathol. 59(1) , 1-10, (1990)
The transition of adult rat aortic smooth muscle cells from a contractile to a synthetic phenotype during the first week of primary culture on a substrate of fibronectin in serum-free medium was studi...
J. Cell Physiol. 172(2) , 192-9, (1997)
Cytoskeleton not only controls cell morphology but also regulates cell growth, migration, differentiation, and gene expression, events which are fundamental to embryogenesis, carcinogenesis, and wound...