1-Aminocyclobutanecarboxylic acid

Suppliers

Names

[ CAS No. ]:
22264-50-2

[ Name ]:
1-Aminocyclobutanecarboxylic acid

[Synonym ]:
N-Methylquipazine dimaleate
1-amino-cyclobutanecarboxylicaci
ACBC-OH
MFCD00661068
cb1700
AC4C-OH
Cyclobutanecarboxylic acid, 1-amino-
1-Aminocyclobutaneca
1-Amino-1-carboxycyclobutane
1-Amino-1-cyclobutanecarboxylic acid
1-aminocyclobutane-1-carboxylic acid
1,1-ACCB
1-Aminocyclobutanecarboxylic acid
1-Aminocyclobutan-1-carboxylic acid
aminocyclobutane carboxylic acid
ACBC

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
241.1±23.0 °C at 760 mmHg

[ Melting Point ]:
261ºC (dec.)

[ Molecular Formula ]:
C5H9NO2

[ Molecular Weight ]:
115.131

[ Flash Point ]:
99.6±22.6 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
63.32000

[ LogP ]:
-0.62

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.540

[ Storage condition ]:
Store at RT

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU1336000
CHEMICAL NAME :
Cyclobutanecarboxylic acid, 1-amino-
CAS REGISTRY NUMBER :
22264-50-2
BEILSTEIN REFERENCE NO. :
2802253
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H9-N-O2
MOLECULAR WEIGHT :
115.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
GU1336000

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • CYCLOBUTANE-1,1-DICARBOXYLIC ACID MONOAMIDE
  • NSC 51773

DownStream

  • Methyl 1-aminocyclobutanecarboxylate hydrochloride
  • 1-hydroxycyclobutanecarboxylic acid
  • 7-oxa-5-azaspiro[3.4]octane-6,8-dione
  • N-Boc-1-aminocyclobutanecarboxylic acid
  • Cyclobutanone
  • 1-aminocyclobutane-1-carbonyl chloride,hydrochloride

Preparation


Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

[Change in the level of 1-aminochloropropane-1-carbonic acid. Activity of a protein inhibitor of polygalacturonase, intensity of formation of oligouronides in apples during ripening and treatment with haloethane derivatives and aminoethoxyvinylglycine].

Prikl. Biokhim. Mikrobiol. 39(4) , 461-4, (2003)

We studied changes in the intensity of ethylene release and accumulation of 1-aminocyclopropane-1-carboxylic acid during ripening of two apple varieties characterized by various physiological states a...

Glycine antagonist action of 1-aminocyclobutane-1-carboxylate (ACBC) in Xenopus oocytes injected with rat brain mRNA.

Eur. J. Pharmacol. 167(2) , 291-4, (1989)

ACBC has been reported to have the binding profile of an antagonist at the glycine site of the NMDA receptor. In Xenopus oocytes injected with rat brain mRNA, we have confirmed the antagonist action o...

Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme.

Chem. Biol. 5(1) , 49-57, (1998)

The chemical mechanism of the final step of ethylene biosynthesis (the conversion of 1-aminocyclopropanecarboxylic acid, ACC, to ethylene by ACC oxidase, the ethylene-forming enzyme, EFE) is poorly un...


More Articles

Related Compounds

  • 1-Aminocyclobutanecarboxylic acid
  • N-Boc-1-aminocyclobutanecarboxylic acid
  • 1-aminocyclobutanecarboxylic acid benzyl ester
  • 1-Aminocyclobutanecarboxylic acid hydrochloride (1:1)
  • 1-aminocyclobutanecarboxylic acid chloride hydrochloride
  • 1-aminocyclobutanecarboxylic Acid Methyl ester-hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine