1-Aminocyclobutanecarboxylic acid

Modify Date: 2024-01-02 21:42:17

1-Aminocyclobutanecarboxylic acid structure	Common Name	1-Aminocyclobutanecarboxylic acid
	CAS Number	22264-50-2	Molecular Weight	115.131
	Density	1.3±0.1 g/cm3	Boiling Point	241.1±23.0 °C at 760 mmHg
	Molecular Formula	C₅H₉NO₂	Melting Point	261ºC (dec.)
	MSDS	Chinese USA	Flash Point	99.6±22.6 °C
	Symbol	GHS07	Signal Word	Warning

Use of 1-Aminocyclobutanecarboxylic acid

1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1[1].

Name	1-Aminocyclobutanecarboxylic acid
Synonym	More Synonyms

Description	1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Atsushi Inanobe, et al. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron. 2005 Jul 7;47(1):71-84.

Density	1.3±0.1 g/cm3
Boiling Point	241.1±23.0 °C at 760 mmHg
Melting Point	261ºC (dec.)
Molecular Formula	C₅H₉NO₂
Molecular Weight	115.131
Flash Point	99.6±22.6 °C
Exact Mass	115.063332
PSA	63.32000
LogP	-0.62
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.540
Storage condition	Store at RT

1-Aminocyclobutanecarboxylic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU1336000

CHEMICAL NAME :: Cyclobutanecarboxylic acid, 1-amino-

CAS REGISTRY NUMBER :: 22264-50-2

BEILSTEIN REFERENCE NO. :: 2802253

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H9-N-O2

MOLECULAR WEIGHT :: 115.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GU1336000
HS Code	2922499990

CYCLOBUTANE-1,1...

CAS#:845621-11-6

~70%

1-Aminocyclobut...

CAS#:22264-50-2

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2005/19158 A1, 2005 ; Location in patent: Page/Page column 18 ;

NSC 51773

CAS#:89691-88-3

~40%

1-Aminocyclobut...

CAS#:22264-50-2

Literature: Pirrung; Cao; Chen Journal of Organic Chemistry, 1995 , vol. 60, # 18 p. 5790 - 5794

N/A

CAS#:117488-20-7

~76%

1-Aminocyclobut...

CAS#:22264-50-2

Literature: Gaoni, Yehiel Organic Preparations and Procedures International, 1995 , vol. 27, # 2 p. 185 - 212

Precursor 2
CAS#:845621-11-6 CYCLOBUTANE-1,1... CAS#:89691-88-3 NSC 51773
DownStream 6
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CAS#:1191-95-3 Cyclobutanone CAS#:735287-43-1 1-aminocyclobut...

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

[Change in the level of 1-aminochloropropane-1-carbonic acid. Activity of a protein inhibitor of polygalacturonase, intensity of formation of oligouronides in apples during ripening and treatment with haloethane derivatives and aminoethoxyvinylglycine].

Prikl. Biokhim. Mikrobiol. 39(4) , 461-4, (2003)

We studied changes in the intensity of ethylene release and accumulation of 1-aminocyclopropane-1-carboxylic acid during ripening of two apple varieties characterized by various physiological states a...

Glycine antagonist action of 1-aminocyclobutane-1-carboxylate (ACBC) in Xenopus oocytes injected with rat brain mRNA.

Eur. J. Pharmacol. 167(2) , 291-4, (1989)

ACBC has been reported to have the binding profile of an antagonist at the glycine site of the NMDA receptor. In Xenopus oocytes injected with rat brain mRNA, we have confirmed the antagonist action o...

Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme.

Chem. Biol. 5(1) , 49-57, (1998)

The chemical mechanism of the final step of ethylene biosynthesis (the conversion of 1-aminocyclopropanecarboxylic acid, ACC, to ethylene by ACC oxidase, the ethylene-forming enzyme, EFE) is poorly un...

N-Methylquipazine dimaleate

1-amino-cyclobutanecarboxylicaci

ACBC-OH

MFCD00661068

cb1700

AC4C-OH

Cyclobutanecarboxylic acid, 1-amino-

1-Aminocyclobutaneca

1-Amino-1-carboxycyclobutane

1-Amino-1-cyclobutanecarboxylic acid

1-aminocyclobutane-1-carboxylic acid

1,1-ACCB

1-Aminocyclobutanecarboxylic acid

1-Aminocyclobutan-1-carboxylic acid

aminocyclobutane carboxylic acid

ACBC

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1-Aminocyclobutanecarboxylic acid
Price: ￥398.0/1g ￥1568.0/5g
Purity: 97.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 1-Aminocyclobutanecarboxylic acid
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-Aminocyclobutane-1-carboxylic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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1-Aminocyclobutanecarboxylic acid

Use of 1-Aminocyclobutanecarboxylic acid

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