6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE

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Names

[ CAS No. ]:
2240-25-7

[ Name ]:
6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE

[Synonym ]:
EINECS 218-806-8
1,4-Naphthalenedione, 2-chloro-3-[(2-methylpropyl)amino]-
5-bromoycytosine
4-Amino-5-bromo-2-hydroxypyrimidine
2-chloro-3-(isobutylamino)-1,4-dihydronaphthalene-1,4-dione
MFCD00056025
4-amino-5-bromopyrimidin-2-ol
5-Bromocytosine
bromocytosine
4-amino-5-bromo-1H-pyrimidin-2-one
6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE
2-Chloro-3-(isobutylamino)-1,4-naphthoquinone
F3096-1966

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
359.5±42.0 °C at 760 mmHg

[ Melting Point ]:
240-243ºC

[ Molecular Formula ]:
C4H4BrN3O

[ Molecular Weight ]:
190.00

[ Flash Point ]:
171.2±27.9 °C

[ Exact Mass ]:
263.071320

[ PSA ]:
72.03000

[ LogP ]:
3.14

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.583

[ Water Solubility ]:
Soluble in formic acid (50 mg/ml).

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H317-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-37/38-41-43-48-20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Structure-activity relationships of beta-D-(2S,5R)- and alpha-D-(2S,5S)-1,3-oxathiolanyl nucleosides as potential anti-HIV agents.

J. Med. Chem. 36(18) , 2627-38, (1993)

The beta-D-(2S,5R)- and alpha-D-(2S,5S)-1,3-oxathiolanylpyrimidine and -purine nucleosides with natural nucleoside configuration were synthesized and evaluated against HIV-1 in human peripheral blood ...

Formation of intrastrand cross-link products between cytosine and adenine from UV irradiation of d((Br)CA) and duplex DNA containing a 5-bromocytosine.

J. Am. Chem. Soc. 127(40) , 13969-77, (2005)

Here, we showed that Pyrex-filtered UV light irradiation of d((Br)CA) gave rise to three types of intrastrand cross-link products, that is, d(C[5-N6]A), d(C[5-2]A), and d(C[5-8]A), where the C5 carbon...

Lifetime regulation of the charge-separated state in DNA by modulating the oxidation potential of guanine in DNA through hydrogen bonding.

J. Am. Chem. Soc. 126(40) , 12843-6, (2004)

A series of naphthalimide (NI)- and 5-bromocytosine ((br)C)-modified oligodeoxynucleotides (ODNs) were prepared, and their lifetimes of the charge-separated states during the photosensitized one-elect...


More Articles


Related Compounds

  • 5-BROMOPYRIMIDIN-2(1H)-ONE HYDROBROMIDE
  • 6-AMINO-5-BROMOPYRIMIDIN-4(3H)-ONE
  • 6-amino-5-(2-hydroxypropyl)-2-sulfanylidene-1H-pyrimidin-4-one
  • 6-amino-5-[(2-methylpiperidin-1-yl)methyl]-1H-pyrimidin-2-one
  • 6-Amino-5-nitroso-1-phenyl-2-[(phenylmethyl)thio]pyrimidin-4(1H)-one
  • 6-Amino-5-nitroso-1-pentyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-sulfamoylthiophene-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-fluoro-1-benzothiophene-2-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-acetamido-4-fluorobenzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-fluoro-5-(trifluoromethyl)benzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-{[(tert-butoxy)carbonyl](ethyl)amino}acetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2S)-2-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]propanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2S)-3-methyl-2-(trifluoroacetamido)butanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-[(methylcarbamoyl)amino]benzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 6,7,8,9-tetrahydro-5H-benzo[7]annulene-5-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(3-methoxyphenyl)-2-methylpropanoate
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