L-Pro-ol

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Names

[ CAS No. ]:
23356-96-9

[ Name ]:
L-Pro-ol

[Synonym ]:
2-Pyrrolidinemethanol
EINECS 245-605-2
H-L-PRO-OL
MFCD00005255
(S)-(+)-Prolinol
2-Pyrrolidinylmethanol
DL-Prolinol
Pyrrolidine, 2-(hydroxymethyl)-
2-Pyrrolidinemethanol, (2S)-
(S)-(+)-2-(Hydroxymethyl)Pyrrolidine
(2S)-pyrrolidin-2-ylmethanol
L-Prolinol
(2S)-2-Pyrrolidinylmethanol
(S)-Pyrrolidin-2-ylmethanol
H-PROLINOL
pyrrolidin-2-ylmethanol
Prolinol
L-Pro-ol
rac-prolinol
(S)-Prolinol
(2S)-2-Pyrrolidinemethanol
(S)-(+)-2-Pyrrolidinemethanol
H-PRO-OL
L(+)-Prolinol
(2S)-prolinol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
211.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H11NO

[ Molecular Weight ]:
101.147

[ Flash Point ]:
86.1±0.0 °C

[ Exact Mass ]:
101.084061

[ PSA ]:
32.26000

[ LogP ]:
-0.67

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.455

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Proline
  • L-Pyroglutamicacid
  • (S)-(1-(4-methoxybenzyl)pyrrolidin-2-yl)methanol
  • L-(+)Sodium glutamate
  • 5-chloro-4-oxopentanoic acid methyl ester
  • 3-(6-oxo-5R-phenyl-5,6-dihydro-2H-[1,4]oxazin-3-yl)propanoic acid methyl ester

DownStream

  • [1-(4-nitrophenyl)pyrrolidin-2-yl]methanol
  • ABT-239
  • Cyclohexanone
  • Pyrrolidine, 1-(dichloroacetyl)-2-ethenyl-, (S)- (9CI)
  • 1-[(2S)-2-Pyrrolidinylmethyl]pyrrolidine
  • 2-Pyrrolidinemethanol, 1-(trifluoroacetyl)-, (2S)- (9CI)
  • furan-2-yl-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]methanone
  • (2S)-1-(2-azido-5-methylbenzoyl)pyrrolidine-2-carbaldehyde
  • [(2S)-1-(4-bromohexa-2,4-dienyl)pyrrolidin-2-yl]methanol
  • N-Methyl-L-prolinol

Preparation


Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...

Chiral Diphenylprolinol TES ether promoted conjugate addition-aldol-dehydration reactions between alpha,beta-unsaturated aldehydes and 2-N-protected amino benzaldehydes.

Org. Lett. 9(6) , 965-8, (2007)

A conjugate addition-aldol-dehydration reaction of alpha,beta-unsaturated aldehydes with 2-N-protected amino benzaldehydes has been developed. The process is promoted by (S)-diphenylprolinol TES ether...

Asymmetric alkynylation of aldehydes with propiolates without high reagent loading and any additives.

Org. Biomol. Chem. 9(12) , 4425-8, (2011)

The asymmetric alkynylation of aliphatic and aromatic aldehydes with propiolates was mediated by dialkylzinc and a novel prolinol catalyst without high reagent loading and any additives, such as Ti(Oi...


More Articles

Related Compounds

  • L-Pro-ol
  • L-Pro-L-Leu-Aib-D-Iva-L-Glu-L-Vol
  • L-Pro-L-His-L-Phe-L-Arg-Gly-NH2
  • (2S)-3-(3,4-dihydroxyphenyl)-2-[[(2S)-3-(3,4-dihydroxyphenyl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]propanoic acid
  • D-prolinol
  • N-Boc-L-Prolinol
  • 2-cyclohexyl-N-cyclopropylalanine
  • 4-Acetylamino-2-fluoro-5-nitro-benzoic acid
  • tert-butyl 1-(1-hydroxy-2-(1-methyl-1H-pyrazol-3-ylamino)-2-oxoethyl)-cyclobutylcarbamate
  • 5'-O-tert-Butyldimethylsilyl-2'-deoxy-2'-fluoro-2'-C-methyluridine
  • 2-(7-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid
  • Phenylmethyl (3S,4S)-3-amino-4-(2-methoxyethoxy)-1-pyrrolidinecarboxylate
  • Methyl 4-amino-1-[2-(4-methoxycarbonylphenoxy)ethyl]pyrazole-3-carboxylate
  • 3-Cyclopropyl-1-(pyridin-4-yl)propan-1-ol
  • 2-({[2-(Trifluoromethyl)phenyl]methyl}amino)pyridine-3-carbonitrile
  • 1-(2-fluoro-5-methylphenyl)-1H-1,2,3-triazole-4-carbaldehyde
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