8-Gingerol
Suppliers
Names
[ CAS No. ]:
23513-08-8
[ Name ]:
8-Gingerol
[Synonym ]:
8-Gingerol
(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-
(5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one
(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
476.4±35.0 °C at 760 mmHg
[ Melting Point ]:
30 - 32 °C
[ Molecular Formula ]:
C19H30O4
[ Molecular Weight ]:
322.439
[ Flash Point ]:
162.6±19.4 °C
[ Exact Mass ]:
322.214417
[ PSA ]:
66.76000
[ LogP ]:
3.55
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.517
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
methanol: soluble1mg/mL, clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JR4362000
- CHEMICAL NAME :
- 3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-(+)-
- CAS REGISTRY NUMBER :
- 23513-08-8
- LAST UPDATED :
- 199503
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C19-H30-O4
- MOLECULAR WEIGHT :
- 322.49
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 25,231,1990
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317
[ Precautionary Statements ]:
P280
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
43
[ Safety Phrases ]:
36/37
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3.0
[ RTECS ]:
JR4362000
[ HS Code ]:
29145019
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 986-987 , 69-84, (2015)
Gua-Lou-Gui-Zhi decoction (GLGZD) is a classical formula of traditional Chinese medicine, which has been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury. In this study...
J. Pharm. Pharmacol. 67(4) , 583-96, (2015)
To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and ...
Bioorg. Med. Chem. 18 , 3345-51, (2010)
Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the hu...