8-Gingerol

Modify Date: 2024-01-04 14:39:37

8-Gingerol structure	Common Name	8-Gingerol
	CAS Number	23513-08-8	Molecular Weight	322.439
	Density	1.1±0.1 g/cm3	Boiling Point	476.4±35.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₃₀O₄	Melting Point	30 - 32 °C
	MSDS	Chinese USA	Flash Point	162.6±19.4 °C
	Symbol	GHS07	Signal Word	Warning

Use of 8-Gingerol

8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].

Name	[8]-Gingerol
Synonym	More Synonyms

Description	8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Infection Research Areas >> Inflammation/Immunology
References	[1]. Dedov, V.N., et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6), 793-798 (2002). [2]. Chrubasik, S., et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9), 684-701 (2005).

Description

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

References

[1]. Dedov, V.N., et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6), 793-798 (2002).

[2]. Chrubasik, S., et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9), 684-701 (2005).

Density	1.1±0.1 g/cm3
Boiling Point	476.4±35.0 °C at 760 mmHg
Melting Point	30 - 32 °C
Molecular Formula	C₁₉H₃₀O₄
Molecular Weight	322.439
Flash Point	162.6±19.4 °C
Exact Mass	322.214417
PSA	66.76000
LogP	3.55
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.517
Storage condition	2-8°C
Water Solubility	methanol: soluble1mg/mL, clear, colorless

8-Gingerol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JR4362000

CHEMICAL NAME :: 3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-(+)-

CAS REGISTRY NUMBER :: 23513-08-8

LAST UPDATED :: 199503

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H30-O4

MOLECULAR WEIGHT :: 322.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 25,231,1990

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P280
Hazard Codes	Xi: Irritant;
Risk Phrases	43
Safety Phrases	36/37
RIDADR	NONH for all modes of transport
WGK Germany	3.0
RTECS	JR4362000
HS Code	29145019

Precursor 9
CAS#:1135-24-6 ferulic acid CAS#:502-44-3 6-Hexanolactone CAS#:4547-43-7 6-hydroxyhexano... CAS#:1135-23-5 dihydroferulic acid
CAS#:57371-44-5 3-(4-(Benzyloxy... CAS#:1700-32-9 methyl 4-benzyl... CAS#:56024-44-3 Methyl 3-(4-Hyd... CAS#:69172-20-9 3-(3-methoxy-4-...
CAS#:146830-53-7 2-[2-(4-Hydroxy...
DownStream 0

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Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7.

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Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the hu...

8-Gingerol

(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone

3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-

(5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one

(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone

BioBioPha
China
Product Name: 8-Gingerol
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 8-Gingerol
Price: ￥938.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 8-Gingerol
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 8-Gingerol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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8-Gingerol

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