DL-O-Tyrosine

Names

[ Name ]:
DL-O-Tyrosine

[Synonym ]:
2,5-Diaminopentanoic acid
EINECS 219-134-8
2-Amino-3-(2-hydroxyphenyl)propionic Acid
L-2,5-Diaminopentanoic acid
MFCD00021725
D,L-o-tyrosine
DL-o-Tyrosine

Chemical & Physical Properties

[ Density]:
1.333g/cm3

[ Boiling Point ]:
369ºC at 760mmHg

[ Melting Point ]:
260ºC

[ Molecular Formula ]:
C₉H₁₁NO₃

[ Molecular Weight ]:
181.18900

[ Flash Point ]:
177ºC

[ Exact Mass ]:
181.07400

[ PSA ]:
83.55000

[ LogP ]:
1.04690

[ Vapour Pressure ]:
5.14E-18mmHg at 25°C

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
Soluble in water, and DMSO (Heated).

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP2285000

CHEMICAL NAME :: o-Tyrosine, DL-

CAS REGISTRY NUMBER :: 2370-61-8

LAST UPDATED :: 197901

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H11-N-O3

MOLECULAR WEIGHT :: 181.21

WISWESSER LINE NOTATION :: QVYZ1R BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02426

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YP2285000

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Ion-pairing reversed-phase liquid chromatography fractionation in combination with isotope labeling reversed-phase liquid chromatography–mass spectrometry for comprehensive metabolome profiling

J. Chromatogr. A. 1218(23) , 3689-94, (2011)

We report a novel two-dimensional (2D) separation strategy aimed at improving the detectability of liquid chromatography mass spectrometry (LC–MS) for metabolome analysis. It is based on the use of io...

Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control.

Cancer Res. 72(5) , 1043-50, (2012)

Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-d...

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

J. Biol. Chem. 274(49) , 34621-8, (1999)

Oxidative stress is implicated in the death of dopaminergic neurons in Parkinson's disease and in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) model of Parkinson's disease. Oxidative speci...

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