6-Hydroxyindole

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Names

[ CAS No. ]:
2380-86-1

[ Name ]:
6-Hydroxyindole

[Synonym ]:
indolol
6-hydroxy-1h-indole
1H-Indol-6-ol
6-Hydroxyindole
EINECS 417-020-4
indol-6-ol
6-monohydroxyindole
6-hydroxy-indole
6-indolol
MFCD00152101

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
343.2±15.0 °C at 760 mmHg

[ Melting Point ]:
124-130 °C

[ Molecular Formula ]:
C8H7NO

[ Molecular Weight ]:
133.15

[ Flash Point ]:
161.4±20.4 °C

[ Exact Mass ]:
133.052765

[ PSA ]:
36.02000

[ LogP ]:
1.41

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.739

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H317-H318-H411

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R22;R41;R43;R51/53

[ Safety Phrases ]:
S37/39-S26-S61-S24-S2

[ RIDADR ]:
UN 3077

[ Hazard Class ]:
9.0

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-[2-(2-nitro-4-phenylmethoxyphenyl)ethenyl]pyrrolidine
  • 6-Benzyloxyindole
  • 6-Methoxyindole
  • 6-benzyloxy-5,7-dichloro-1H-indole
  • [1-(2,2-dimethylpropanoyl)indol-6-yl] 2-chloroacetate
  • Ethenamine, N,N-dimethyl-2-[2-nitro-4-(phenylmethoxy)phenyl]-, (E)
  • 4-Benzyloxy-2-nitrotoluene
  • 3-Nitrophenol

DownStream

  • 6-Methoxyindole
  • 6-Ethoxy-1H-indole
  • tert-butyl-(1H-indol-6-yloxy)-dimethylsilane
  • 6-(3-CHLORO-PROPOXY)-1H-INDOLE

Articles

Determination of selected synthetic cannabinoids and their metabolites by micellar electrokinetic chromatography--mass spectrometry employing perfluoroheptanoic acid-based micellar phase.

Talanta 150 , 568-76, (2016)

Perfluoroheptanoic acid was employed as a volatile micellar phase in background electrolyte for micellar electrokinetic chromatography-tandem mass spectrometry separation and determination of 15 selec...

Inhibitory effect of hydroxyindoles and their analogues on human melanoma tyrosinase.

Z. Naturforsch., C, J. Biosci. 65 , 49-54, (2010)

A recent study showed that N-acylserotonin derivatives have strong inhibitory activity against tyrosinase. To clarify the role of the 5-hydroxy group in the indole ring, 2-, 4-, 5-, 6-, and 7-hydroxyi...

Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent.

PLoS ONE 8(1) , e54767, (2013)

Human UDP-glucuronosyltransferases (UGTs) are important enzymes in metabolic elimination of endo- and xenobiotics. It was recently shown that addition of fatty acid free bovine serum albumin (BSA) sig...


More Articles

Related Compounds

  • N-Boc-6-Hydroxyindole
  • 4-Bromo-6-hydroxyindole
  • 5-methoxy-6-hydroxyindole
  • 5-acetoxy-6-hydroxyindole
  • 6-hydroxyindole-2-sulfonamide
  • 2-carbomethoxy-6-hydroxyindole