4-Hydroxyindole

Suppliers

Names

[ Name ]:
4-Hydroxyindole

[Synonym ]:
1H-Indol-4-ol
4-Hydroxylndole
1H-Indol-7-ol
EINECS 219-177-2
indol-4-ol
7-Hydroxyindol
7-HYDROXYLINDOLE
4-hydroxy-indole
INDOL-7-OL
7-HYDROXY-1H-INDOLE
7-monohydroxyindole
7-hydroxyindole
1H-INDOLE-4-OL
4-Hydroxxyindole
7-Indolol
MFCD00005667
4-Hydroxyindole
4-hydroxy-1H-indole
4-INDOLOL

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
343.2±15.0 °C at 760 mmHg

[ Melting Point ]:
97-99 °C(lit.)

[ Molecular Formula ]:
C₈H₇NO

[ Molecular Weight ]:
133.147

[ Flash Point ]:
161.4±20.4 °C

[ Exact Mass ]:
133.052765

[ PSA ]:
36.02000

[ LogP ]:
1.41

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.739

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-benzyloxy-6-nitrophenyl acetaldehyde
3-nitro-2-vinylphenol
2-BENZYLOXY-6-NITROMETHYLCYANOBENZENE
1,5,6,7-Tetrahydro-4H-indol-4-one
4-acetoxy-N-tosylindole
Indolin-4-ol
2-Bromo-3-nitrophenol
4-hydroxy-1-methoxycarbonylindole
6-benzyloxy-2-nitrotoluene
2,6-Dinitrotoluene

DownStream

2-bromo-N-[2-[4-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-4-methylcyclohexyl]propan-2-yl]acetamide
(+/-)-PINDOBIND
4-Methoxyindole
4-Methoxy-1H-indole-3-carbaldehyde
5-Methyl-1H-indol-4-ol
1H-Indol-4-ol, 5-[(dimethylamino)Methyl]-
1-amino-3-(1H-indol-4-yloxy)propan-2-ol
5-methoxytryptoline
4-HYDROXYINDOLE-3-CARBOXYLIC ACID
4-Ethoxy-1H-indole

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 68-76, (2014)

• Optimization of a suitable extraction protocol for alkylindoles and their metabolites from biological fluids. • Detection of alkylindoles and their metabolites by means of the GC/MS method adopted b...

Validation and application of an UPLC-MS/MS method for the quantification of synthetic cannabinoids in urine samples and analysis of seized materials from the Portuguese market.

Forensic Sci. Int. 243 , 117-25, (2014)

An UPLC-MS/MS method using ESI+ionization and MRM was developed and fully validated according to international guidelines for the qualitative and quantitative analysis of nine synthetic cannabinoids a...

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

Drug Metab. Dispos. 38(3) , 386-95, (2010)

We have examined the glucuronidation of psilocin, a hallucinogenic indole alkaloid, by the 19 recombinant human UDP-glucuronosyltransferases (UGTs) of subfamilies 1A, 2A, and 2B. The glucuronidation o...

4-Hydroxyindole
N-Boc-4-Hydroxyindole
N-tosyl-4-hydroxyindole
2-Cyano-4-hydroxyindole
6-Bromo-4-hydroxyindole
3-CYANO-4-HYDROXYINDOLE
3-[4-Methyl-3-(trifluoromethyl)phenyl]propan-1-ol
4-[4-Methyl-3-(trifluoromethyl)phenyl]butan-2-one
4-(2-Bromopropyl)-1-methyl-2-(trifluoromethyl)benzene
4-[4-methyl-3-(trifluoromethyl)phenyl]-1H-pyrazole
2,2-Difluoro-1-[4-methyl-3-(trifluoromethyl)phenyl]ethan-1-one
5-[4-Methyl-3-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one
2-[4-Methyl-3-(trifluoromethyl)phenoxy]ethan-1-amine
methyl (3R)-3-hydroxy-3-[4-(propan-2-yloxy)phenyl]propanoate
4-(2-tert-butyl-2H-1,2,3,4-tetrazol-5-yl)butan-2-ol
2-(Quinoxalin-2-yl)cyclopropane-1-carboxylic acid