4-Hydroxyindole

Modify Date: 2024-01-02 19:33:55

4-Hydroxyindole Structure
4-Hydroxyindole structure
Common Name 4-Hydroxyindole
CAS Number 2380-94-1 Molecular Weight 133.147
Density 1.3±0.1 g/cm3 Boiling Point 343.2±15.0 °C at 760 mmHg
Molecular Formula C8H7NO Melting Point 97-99 °C(lit.)
MSDS Chinese USA Flash Point 161.4±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-Hydroxyindole


4-Hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. 4-Hydroxyindole is an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers[1].

 Names

Name 4-hydroxyindole
Synonym More Synonyms

 4-Hydroxyindole Biological Activity

Description 4-Hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. 4-Hydroxyindole is an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers[1].
Related Catalog
References

[1]. Nenad Manevski, et al. Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases. Drug Metab Dispos. 2010 Mar;38(3):386-95.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 343.2±15.0 °C at 760 mmHg
Melting Point 97-99 °C(lit.)
Molecular Formula C8H7NO
Molecular Weight 133.147
Flash Point 161.4±20.4 °C
Exact Mass 133.052765
PSA 36.02000
LogP 1.41
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.739
Storage condition 0-6°C
Water Solubility slightly soluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles8

More Articles
Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 68-76, (2014)

• Optimization of a suitable extraction protocol for alkylindoles and their metabolites from biological fluids. • Detection of alkylindoles and their metabolites by means of the GC/MS method adopted b...

Validation and application of an UPLC-MS/MS method for the quantification of synthetic cannabinoids in urine samples and analysis of seized materials from the Portuguese market.

Forensic Sci. Int. 243 , 117-25, (2014)

An UPLC-MS/MS method using ESI+ionization and MRM was developed and fully validated according to international guidelines for the qualitative and quantitative analysis of nine synthetic cannabinoids a...

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

Drug Metab. Dispos. 38(3) , 386-95, (2010)

We have examined the glucuronidation of psilocin, a hallucinogenic indole alkaloid, by the 19 recombinant human UDP-glucuronosyltransferases (UGTs) of subfamilies 1A, 2A, and 2B. The glucuronidation o...

 Synonyms

1H-Indol-4-ol
4-Hydroxylndole
1H-Indol-7-ol
EINECS 219-177-2
indol-4-ol
7-Hydroxyindol
7-HYDROXYLINDOLE
4-hydroxy-indole
INDOL-7-OL
7-HYDROXY-1H-INDOLE
7-monohydroxyindole
7-hydroxyindole
1H-INDOLE-4-OL
4-Hydroxxyindole
7-Indolol
MFCD00005667
4-Hydroxyindole
4-hydroxy-1H-indole
4-INDOLOL
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