7,10-Dimethylbenzo[c]acridine
Names
[ CAS No. ]:
2381-40-0
[ Name ]:
7,10-Dimethylbenzo[c]acridine
[Synonym ]:
6,9-Dimethyl-1,2-benzacridine
7,10-Dimethyl-benzo<c>acridin
7,10-Dimethylbenzo[c]acridine
Benz[c]acridine, 7,10-dimethyl-
2,10-Dimethyl-7,8-benzoacridin
7,10-Dimethylbenz<c>acridin
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
470.2±14.0 °C at 760 mmHg
[ Melting Point ]:
147-149ºC(lit.)
[ Molecular Formula ]:
C19H15N
[ Molecular Weight ]:
257.329
[ Flash Point ]:
209.8±12.7 °C
[ Exact Mass ]:
257.120453
[ PSA ]:
12.89000
[ LogP ]:
5.55
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.738
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU3485000
- CHEMICAL NAME :
- Benz(c)acridine, 7,10-dimethyl-
- CAS REGISTRY NUMBER :
- 2381-40-0
- BEILSTEIN REFERENCE NO. :
- 0192194
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C19-H15-N
- MOLECULAR WEIGHT :
- 257.35
- WISWESSER LINE NOTATION :
- T D6 B666 CNJ F J
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 190 mg/kg/16W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - bronchiolar constriction
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg/4W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg/10D-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Kidney
- DOSE/DURATION :
- 80 ug/L
- REFERENCE :
- BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
20/21/22-36/37/38-40
[ Safety Phrases ]:
S22;S26;S36
[ WGK Germany ]:
3
[ RTECS ]:
CU3485000
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%