Z-D-Phe-OH

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Names

[ CAS No. ]:
2448-45-5

[ Name ]:
Z-D-Phe-OH

[Synonym ]:
N-Cbz-D-phenylalanine Z-D-phenylalanine
EINECS 258-154-1
MFCD00063151
L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-
Cbz-D-Phenylalanine
Z-D-phenylalanine
Cbz-protected D-phenylalanine
Phenylalanine, N-[(phenylmethoxy)carbonyl]-
N-CBZ-L-phenylalanine
N-[(Benzyloxy)carbonyl]phenylalanine
(2R)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoic acid
N-Cbz-D-Phenylalanine
Cbz-D-Phe-OH
N-carbobenzyloxy-dl-phenylalanine
N-CARBOBENZYLOXY-D-PHENYLALANINE
Z-D-Phe-OH
(2S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoic acid
N-Carbobenzoxy-D-phenylalanine
Benzyloxycarbonyl-D-phenylalanine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
511.5±50.0 °C at 760 mmHg

[ Melting Point ]:
80-82ºC

[ Molecular Formula ]:
C17H17NO4

[ Molecular Weight ]:
299.321

[ Flash Point ]:
263.1±30.1 °C

[ Exact Mass ]:
299.115753

[ PSA ]:
75.63000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.591

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • D-phenylalanine
  • Benzyl chloroformate
  • Z-D-Phe-ONp
  • benzyl (2S,3R,5R)-5-benzyl-2,3-dimethoxy-2,3-dimethyl-6-oxomorpholine-4-carboxylate
  • N-Cbz-O-benzyl phenylalanine
  • benzyl N-[(2S)-3-bromo-2-hydroxypropyl]carbamate
  • (2S,3R)-benzyl 2,3-dimethoxy-2,3-dimethyl-6-methylenemorpholine-4-carboxylate
  • benzyl (2S,3R,6S)-6-(bromomethyl)-2,3-dimethoxy-2,3-dimethylmorpholine-4-carboxylate
  • Ethanol
  • N-carbobenzyloxy-dl-phenylalanine

DownStream

  • a-methyl-D-phenylalanine
  • D-phenylalanine
  • a-methyl-L-phenylalanine
  • Z-D-Phe-ONp
  • Benzyl [(2R)-1-oxo-3-phenyl-2-propanyl]carbamate
  • H-D-Phe-D-Phe-OH
  • Ubenimex
  • Cbz-D-Phenylalaninol
  • Z-D-Phe-OSu
  • (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclopropylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Effects of metalloendoproteinase inhibitors on secretion and intracellular free calcium in bovine adrenal chromaffin cells.

Biochim. Biophys. Acta 889(1) , 1-5, (1986)

The possible role of metalloendoproteinase in stimulus-secretion coupling in adrenal chromaffin cells was examined using the metalloendoproteinase inhibitors 1,10-phenanthroline and carbobenzoxy-Gly-P...

Mechanism of the binding of Z-L-tryptophan and Z-L-phenylalanine to thermolysin and stromelysin-1 in aqueous solutions.

Biochim. Biophys. Acta 1824(2) , 303-10, (2012)

The chemical shift of the carboxylate carbon of Z-tryptophan is increased from 179.85 to 182.82 ppm and 182.87 ppm on binding to thermolysin and stromelysin-1 respectively. The chemical shift of Z-phe...

Modification of a zinc proteinase from Bacillus mesentericus strain 76 by diethylpyrocarbonate.

Int. J. Pept. Protein Res. 37(4) , 325-30, (1991)

Diethylpyrocarbonate (DEPC) inactivated the neutral zinc proteinase from Bacillus mesentericus strain 76/Bacillus subtilis (MCP 76) by ethoxycarbonylation completely. Exposure of the enzyme to DEPC to...


More Articles

Related Compounds

  • Z-D-Phe-Val-OH
  • Z-D-Phe-Pro-OH
  • Z-D-Phe-Phe-Gly-OH
  • Z-D-Phe(4-F)-OH
  • Z-D-Phe-Phe-Arg(NO2)-OH
  • Z-D-Ala-Phe-OH
  • Tert-butyl 4-aminoquinoline-2-carboxylate
  • 3,4-Dihydro-7-(4-pyrimidinylamino)-2h-pyrido[1,2-a]pyrazine-1,6-dione
  • 6'-Bromo-8'-chloro-4,4-difluoro-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione
  • 3-(3,3-Diethoxypropoxy)azetidine
  • 6-(aminomethyl)-N-methyl-N-(propan-2-yl)pyridin-3-amine
  • 1-[6-(Aminomethyl)-3-pyridinyl]-4-piperidinemethanol
  • 6-(aminomethyl)-N-ethyl-N-methylpyridin-3-amine
  • 6-(aminomethyl)-N-methyl-N-propylpyridin-3-amine
  • 2-{[6-(Aminomethyl)pyridin-3-yl](methyl)amino}ethan-1-ol
  • 5-[(Propan-2-yl)amino]pyridine-2-carbonitrile
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