Geniposide

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Names

[ CAS No. ]:
24512-63-8

[ Name ]:
Geniposide

[Synonym ]:
Olea europaea L
Methyl (1S)-1-(β-D-glucopyranosyloxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
Geniposide
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-, methyl ester, (1S,4aS,7aS)-
Geniposidic
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-, methyl ester, (1S)-
Cyclopenta(c)pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-, methyl ester, (1S,4aS,7aS)-
Jasminoidin
Methyl (1S,4aS,7aS)-1-(β-D-glucopyranosyloxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
Genipin 1-glucoside
MFCD00016659

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
641.4±55.0 °C at 760 mmHg

[ Melting Point ]:
161-162ºC

[ Molecular Formula ]:
C17H24O10

[ Molecular Weight ]:
388.366

[ Flash Point ]:
231.5±25.0 °C

[ Exact Mass ]:
388.136932

[ PSA ]:
155.14000

[ LogP ]:
-1.92

[ Vapour Pressure ]:
0.0±4.3 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
?20°C

MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Synthetic Route

Precursor & DownStream

Precursor

  • Geniposidic acid
  • (Trimethylsilyl)diazomethane
  • diazomethane

DownStream

  • Geniposidic acid
  • 4,7-dimethyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-ol

Articles

The effects of notoginsenoside R₁ on the intestinal absorption of geniposide by the everted rat gut sac model.

J. Ethnopharmacol. 142(1) , 136-43, (2012)

Geniposide is derived from Gardenia jasminoides Ellis (Rubiaceae). Its anti-inflammatory, antithrombotic effects as well as its preventive effect against ischemic stroke have been reported. Radix noto...

[Effects of geniposide on SNP-induced apoptosis of chondrocyte and cell cycle].

Zhongguo Gu Shang 26(3) , 232-5, (2013)

To study the effects of Geniposide on SNP(sodium nitroprusside)-induced apoptosis of chondrocyte in vitro and cell cycle.The chondrocyte of three-week-old SD rats were separated and cultivated. The se...

Pharmacokinetics of geniposide by monoclonal antibody-based icELISA in mice after oral administration of Huanglian-Jiedu-Tang.

Biol. Pharm. Bull. 37(9) , 1525-33, (2014)

Geniposide, Geniposide, the main active component in extracts of Gardenia jasminoides ELLIS., is one of the main components of Huanglian-Jiedu-Tang (HJT). This study aimed to validate an indirect comp...


More Articles


Related Compounds

  • Geniposide
  • Pentaacetyl geniposide