Antazoline Hydrochloride
Suppliers
Names
[ CAS No. ]:
2508-72-7
[ Name ]:
Antazoline Hydrochloride
[Synonym ]:
Antazoline Hydrochloride
hydrochloride salt of antazoline
Antazoline HCl
UNII-FP8Q8F72JH
Fenazolina
Antistine hydrochloride
Histazine
2-(N-Benzylanilinomethyl)-2-imidazoline Hydrochloride
N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline hydrochloride (1:1)
Antazolinium chloratum
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-aniline,hydrochloride
MFCD00058145
1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, hydrochloride (1:1)
EINECS 219-719-8
Phenazoline hydrochloride
N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-anilin,Hydrochlorid
Antazoline (hydrochloride)
Chemical & Physical Properties
[ Boiling Point ]:
475.5ºC at 760 mmHg
[ Melting Point ]:
238 °C
[ Molecular Formula ]:
C17H20ClN3
[ Molecular Weight ]:
301.814
[ Flash Point ]:
241.4ºC
[ Exact Mass ]:
301.134583
[ PSA ]:
27.63000
[ LogP ]:
3.26130
[ Vapour Pressure ]:
3.31E-09mmHg at 25°C
[ Storage condition ]:
Store at RT
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NJ2150000
- CHEMICAL NAME :
- 2-Imidazoline, 2-((N-benzylanilino)methyl)-, hydrochloride
- CAS REGISTRY NUMBER :
- 2508-72-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H19-N3.Cl-H
- MOLECULAR WEIGHT :
- 301.85
- WISWESSER LINE NOTATION :
- T5M CN BUTJ B1NR&1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - irritability Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 10,338,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 17100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,313,1958
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NJ2150000
[ HS Code ]:
2933290090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933290090
[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
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Supercritical fluid chromatography (SFC) is drawing considerable interest as separation technique in the pharmaceutical industry. The technique is already well established in chiral separations both a...
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