Antazoline Hydrochloride

Modify Date: 2025-08-25 15:54:06

Antazoline Hydrochloride Structure
Antazoline Hydrochloride structure
Common Name Antazoline Hydrochloride
CAS Number 2508-72-7 Molecular Weight 301.814
Density N/A Boiling Point 475.5ºC at 760 mmHg
Molecular Formula C17H20ClN3 Melting Point 238 °C
MSDS Chinese USA Flash Point 241.4ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Antazoline Hydrochloride


Antazoline hydrochloride is a 1st generation antihistamine with also anticholinergic properties used to relieve nasal congestion and in eye drops.

 Names

Name N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline,hydrochloride
Synonym More Synonyms

 Antazoline Hydrochloride Biological Activity

Description Antazoline hydrochloride is a 1st generation antihistamine with also anticholinergic properties used to relieve nasal congestion and in eye drops.
Related Catalog

 Chemical & Physical Properties

Boiling Point 475.5ºC at 760 mmHg
Melting Point 238 °C
Molecular Formula C17H20ClN3
Molecular Weight 301.814
Flash Point 241.4ºC
Exact Mass 301.134583
PSA 27.63000
LogP 3.26130
Vapour Pressure 3.31E-09mmHg at 25°C
Storage condition Store at RT

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ2150000
CHEMICAL NAME :
2-Imidazoline, 2-((N-benzylanilino)methyl)-, hydrochloride
CAS REGISTRY NUMBER :
2508-72-7
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H19-N3.Cl-H
MOLECULAR WEIGHT :
301.85
WISWESSER LINE NOTATION :
T5M CN BUTJ B1NR&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - irritability Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 10,338,1951
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
17100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,313,1958

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R20/21/22;R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NJ2150000
HS Code 2933290090

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Antazoline Hydrochloride
hydrochloride salt of antazoline
Antazoline HCl
UNII-FP8Q8F72JH
Fenazolina
Antistine hydrochloride
Histazine
2-(N-Benzylanilinomethyl)-2-imidazoline Hydrochloride
N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline hydrochloride (1:1)
Antazolinium chloratum
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-aniline,hydrochloride
MFCD00058145
1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, hydrochloride (1:1)
EINECS 219-719-8
Phenazoline hydrochloride
N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-anilin,Hydrochlorid
Antazoline (hydrochloride)
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