Thymidine,5'-amino-5'-deoxy-

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Names

[ CAS No. ]:
25152-20-9

[ Name ]:
Thymidine,5'-amino-5'-deoxy-

[Synonym ]:
5'-Amino-5'-deoxy-D-thymidine
5'-amino-3'-hydroxythymidine
5'-amino-5'-deoxy-thymidine
5'-deoxy-5'-aminothymidine
5'-deoxy-5'-amino-deoxythymidine

Chemical & Physical Properties

[ Density]:
1.394 g/cm3

[ Molecular Formula ]:
C10H15N3O4

[ Molecular Weight ]:
241.24

[ Exact Mass ]:
241.10600

[ PSA ]:
110.34000

[ Index of Refraction ]:
1.565

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • Thymidine,5'-azido-5'-deoxy-
  • 5'-O-methanesulfonyl-β-thymidine
  • Thymidine
  • Thymidine,5'-(4-methylbenzenesulfonate)

DownStream

  • 9H-Purin-6-amine,9-(2-deoxy-b-D-threo-pentofuranosyl)-

Articles

Measurement of carbamoylating activity of nitrosoureas and isocyanates by a novel high-pressure liquid chromatography assay.

Biochem. Pharmacol. 35(14) , 2359-65, (1986)

A new assay for carbamoylating activity using reversed phase liquid chromatography (HPLC) is described which offers several advantages over existing assays. A comparison was made of the extent of carb...

Novel acyclic amide-conjugated nucleosides and their analogues.

Nucleosides Nucleotides Nucleic Acids 28 , 103-117, (2009)

An effective one-step synthesis of new amide-conjugated nucleosides and their analogues, in the presence of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM) as the condensin...

Carbamoylation reactions of N-methyl-N'-aryl-N-nitrosoureas and corresponding phenyl isocyanates to 5'-amino-5'-deoxythymidine: importance of carbamoylation in mouse skin carcinogenic processes.

Carcinogenesis 13(4) , 699-702, (1992)

Carbamoylation reactions of N-methyl-N'-aryl-N-nitrosoureas (I-X: X = -OCH3, -CH3, -H, -Cl, and -COCH3) and of their corresponding phenyl isocyanates (II-X: X = -OCH3, -CH3, -H, -Cl and -COCH3) to the...


More Articles


Related Compounds

  • Thymidine,5'-amino-5'-deoxy-,3'-acetate
  • Thymidine,5'-[(bromoacetyl)amino]-5'-deoxy- (9CI)
  • Thymidine,5'-[(chloroacetyl)amino]-5'-deoxy- (9CI)
  • uridineamine
  • Adenosine,5'-amino-5'-deoxy-
  • 5'-[(tetrahydroxy-[1]triphosphoryl)-amino]-5'-deoxy-thymidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (1,4,4-Trifluorocyclohexyl)methanamine
  • 2-(2,4-Dichlorophenoxy)-1-[4-(thian-4-yl)-1,4-diazepan-1-yl]ethan-1-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 3-Pyridinesulfonyl chloride, 2-chloro-5-cyano-4-(difluoromethyl)-
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde