(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

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Names

[ CAS No. ]:
254881-77-1

[ Name ]:
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

[Synonym ]:
(4S)-4-Amino-1-(tert-butoxycarbonyl)-2-methyl-D-proline
1,2-Pyrrolidinedicarboxylic acid, 4-amino-2-methyl-, 1-(1,1-dimethylethyl) ester, (2R,4S)-
N-a-butoxycarbonyl-trans-4-amino-L-prolinemethyl ester
(4S)-4-Amino-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-amino-1,2-pyrrolidinedicarboxylate
trans-4-amino-N-tert-butoxycarbonyl-D-proline methyl ester
1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4S)-
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
370.2±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H20N2O4

[ Molecular Weight ]:
244.288

[ Flash Point ]:
177.7±27.9 °C

[ Exact Mass ]:
244.142303

[ PSA ]:
81.86000

[ LogP ]:
0.18

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.507

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1N-tert-butoxycarbonyl-2(R)-carbomethoxy-4(S)-azidopyrrolidine
  • Di-tert-butyl dicarbonate
  • N-Boc-cis-4-hydroxy-D-proline methyl ester
  • D-Proline, 4-hydroxy-, methyl ester hydrochloride
  • (2R,4R)-Nα-(tert-butoxycarbonyl)-4-(p-toluenesulfonyloxy)proline methyl ester

DownStream

Related Compounds

  • 1-[2-(phenylsulfanyl)ethyl]-1H-1,2,3,4-tetrazole-5-thiol
  • 1-Nitro-3-(5-nitro-2-thiazolyl)-2-imidazolidinone
  • 3-(Azidomethyl)-2-bromo-1-benzothiophene
  • 1-Iodo-3-(2,2,2-trifluoroethyl)bicyclo[1.1.1]pentane
  • (3-Pyridin-4-yloxycyclopentyl)methanamine
  • 2-(3-Chloro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-Azabicyclo[5.1.0]octane hydrochloride
  • 2-(1-methyl-1H-1,2,3-triazol-4-yl)piperidine dihydrochloride
  • (1R,2S)-2-Methylcyclopropanamine hydrochloride
  • 4-(Dimethylamino)-2-phenylpentanenitrile
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