(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

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Names

[ CAS No. ]:
254881-77-1

[ Name ]:
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

[Synonym ]:
(4S)-4-Amino-1-(tert-butoxycarbonyl)-2-methyl-D-proline
1,2-Pyrrolidinedicarboxylic acid, 4-amino-2-methyl-, 1-(1,1-dimethylethyl) ester, (2R,4S)-
N-a-butoxycarbonyl-trans-4-amino-L-prolinemethyl ester
(4S)-4-Amino-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-amino-1,2-pyrrolidinedicarboxylate
trans-4-amino-N-tert-butoxycarbonyl-D-proline methyl ester
1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4S)-
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
370.2±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H20N2O4

[ Molecular Weight ]:
244.288

[ Flash Point ]:
177.7±27.9 °C

[ Exact Mass ]:
244.142303

[ PSA ]:
81.86000

[ LogP ]:
0.18

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.507

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1N-tert-butoxycarbonyl-2(R)-carbomethoxy-4(S)-azidopyrrolidine
  • Di-tert-butyl dicarbonate
  • N-Boc-cis-4-hydroxy-D-proline methyl ester
  • D-Proline, 4-hydroxy-, methyl ester hydrochloride
  • (2R,4R)-Nα-(tert-butoxycarbonyl)-4-(p-toluenesulfonyloxy)proline methyl ester

DownStream

Related Compounds

  • 2-Amino-2-[1-(2-bromo-5-methylphenyl)cyclopropyl]acetic acid
  • 3-amino-2-(1-ethyl-2,3-dihydro-1H-indol-5-yl)propanoic acid
  • 3-Amino-3-(2,2,3,3-tetramethylcyclopropyl)propanoic acid
  • 2-Amino-3-(2-chloro-6-methylpyridin-3-yl)-3-hydroxypropanoic acid
  • 2-amino-3-methyl-3-(1-methyl-3-phenyl-1H-pyrazol-5-yl)butanoic acid
  • 3-(aminomethyl)-5-(1H-pyrazol-1-yl)pentanoic acid
  • 3-Amino-2-(2-methoxy-1,3-thiazol-5-yl)propanoic acid
  • [1-(2-bromo-4-methoxyphenyl)-1H-pyrazol-4-yl]methanamine
  • [(3-Bromo-2,4-dimethylphenyl)methyl](butan-2-yl)amine
  • [(3-Bromo-2,4-dimethylphenyl)methyl](3-methoxypropyl)amine
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