(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

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Names

[ Name ]:
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

[Synonym ]:
(4S)-4-Amino-1-(tert-butoxycarbonyl)-2-methyl-D-proline
1,2-Pyrrolidinedicarboxylic acid, 4-amino-2-methyl-, 1-(1,1-dimethylethyl) ester, (2R,4S)-
N-a-butoxycarbonyl-trans-4-amino-L-prolinemethyl ester
(4S)-4-Amino-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-amino-1,2-pyrrolidinedicarboxylate
trans-4-amino-N-tert-butoxycarbonyl-D-proline methyl ester
1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4S)-
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
370.2±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₂₀N₂O₄

[ Molecular Weight ]:
244.288

[ Flash Point ]:
177.7±27.9 °C

[ Exact Mass ]:
244.142303

[ PSA ]:
81.86000

[ LogP ]:
0.18

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.507

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1N-tert-butoxycarbonyl-2(R)-carbomethoxy-4(S)-azidopyrrolidine
Di-tert-butyl dicarbonate
N-Boc-cis-4-hydroxy-D-proline methyl ester
D-Proline, 4-hydroxy-, methyl ester hydrochloride
(2R,4R)-Nα-(tert-butoxycarbonyl)-4-(p-toluenesulfonyloxy)proline methyl ester

DownStream

Related Compounds

4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methoxybutanamido]-4-methylpentanoic acid
3-[N-ethyl-7-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanamido]propanoic acid
(2S)-3-cyclopropyl-2-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylhexanamido]propanoic acid
(7-Bromo-1,2-benzothiazol-3-yl)methanamine
5-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]-2-fluorobenzoic acid
5-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]methyl}furan-2-carboxylic acid
4-{[2-(ethylcarbamoyl)ethyl]carbamoyl}-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
2-{1-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]pyrrolidin-3-yl}acetic acid
{2-Aminobicyclo[2.2.1]heptan-1-yl}methanesulfonamide
1-{2-aminobicyclo[2.2.1]heptan-1-yl}-N-(propan-2-yl)methanesulfonamide

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