(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline

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Names

[ CAS No. ]:
259212-61-8

[ Name ]:
(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline

[Synonym ]:
(4R)-4-{[tert-Butyl(diphenyl)silyl]oxy}-L-proline
L-4-(tert-butyldiphenylsilyloxy)proline
(2S,4R)-4-(tert-Butyldiphenylsilyloxy)pyrrolidine-2-carboxylic Acid
B3440
(4R)-4-(t-butyldiphenylsilyloxy)-L-proline
trans-4-tertbutlydiphenylsiloxy-L-proline
(4R)-4-(tert-butyldiphenylsiloxy)-L-proline
O-TBDPS-proline
(4R)-4-{[(2-Methyl-2-propanyl)(diphenyl)silyl]oxy}-L-proline
L-Proline, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, (4R)-
trans-4-(tert-Butyldiphenylsilyloxy)-L-proline
4-(tert-butyldiphenylsilyloxy)-pyrrolidine-2-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
468.8±45.0 °C at 760 mmHg

[ Melting Point ]:
198 °C(dec.)

[ Molecular Formula ]:
C21H27NO3Si

[ Molecular Weight ]:
369.530

[ Flash Point ]:
237.3±28.7 °C

[ Exact Mass ]:
369.176025

[ PSA ]:
58.56000

[ LogP ]:
5.23

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.574

MSDS

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Synthetic Route

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Precursor & DownStream

Precursor

  • (2S,4R)-4-(tert-butyldiphenylsiloxy)pyrrolidine-1,2-dicarboxylic acid dibenzyl ester
  • tert-Butyl(chloro)diphenylsilane
  • L-Hydroxyproline
  • (2S,4R)-DIBENZYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE
  • tert-Butyl(diphenyl)silane
  • Z-Hyp-OH

DownStream

Related Compounds

  • (4R)-4-({[tert-butyl(diphenyl)silyl]oxy}methyl)-1,3-oxazolidin-2-one
  • (4R)-4-[tert-butyl(diphenyl)silyl]oxypentan-1-ol
  • (-)-(3S)-4-{[tert-butyl(diphenyl)silyl]oxy}-3-methylbutyl phenyl sulfone
  • di(tert-butyl) (2S,4S)-4-{[tert-butyl(diphenyl)silyl]oxy}-6-oxo-1,2-piperidinedicarboxylate
  • [(R)-3-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-1-HYDROXYMETHYL-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER
  • 4-((tert-butyl(diphenyl)silyl)oxy)cyclohexanecarboxamide
  • 6-{4-[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl}pyridine-3-carbonitrile
  • 6-{4-[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl}pyridine-2-carbonitrile
  • 3-[4-(4,6-dimethylpyrimidin-2-yl)piperazin-1-yl]-6-(3-methyl-1H-pyrazol-1-yl)pyridazine
  • 2-{4-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl}pyridine-3-carbonitrile
  • 3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine
  • 2-{4-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl]piperazin-1-yl}-4,6-dimethylpyrimidine
  • 3-[4-(5-bromopyrimidin-2-yl)piperazin-1-yl]-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine
  • 3-[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine
  • 2-[4-(6-Methoxypyrimidin-4-yl)piperazin-1-yl]pyridine-4-carbonitrile
  • 6-[4-(6-Methoxypyrimidin-4-yl)piperazin-1-yl]pyridine-3-carbonitrile
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