6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione

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Names

[ CAS No. ]:
25983-13-5

[ Name ]:
6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione

[Synonym ]:
6,7-Dichlor-1,4-dihydrochinoxalin-2,3-dion
6,7-Dichloroquinoxaline-2,3-dione
2,3-DICHLORO-4-TRIFLUOROMETHYLTOLUENE
Lopac-D-133
6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione
6,7-dichloroquinoxaline-2,3-diol
2,3-Quinoxalinedione, 6,7-dichloro-1,4-dihydro-
6,7-DICHLORO-1,4-DIHYDRO-2,3-QUINOXALINEDIONE
6,7-dichloro-1,4-dihydroquinoxaline-2,3-dion
MFCD00078575
6,7-Dichlor-2,3-(1H,4H)-chinoxalindion
DCQX
6,7-dichloro-quinoxaline-2,3(1H,4H)-dione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
523.4ºC at 760 mmHg

[ Molecular Formula ]:
C8H4Cl2N2O2

[ Molecular Weight ]:
231.036

[ Flash Point ]:
270.3ºC

[ Exact Mass ]:
229.964981

[ PSA ]:
65.72000

[ LogP ]:
0.81

[ Vapour Pressure ]:
1.43E-11mmHg at 25°C

[ Index of Refraction ]:
1.613

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4,5-dichlorbenzol-1,2-diamin
  • Diethyloxalate
  • 3,4-Dichloro-6-nitroaniline
  • 6,7-Dichloroquinoxaline
  • Oxalic acid
  • ethyl-N-(4,5-dichloro-2-nitro-phenyl)oxamate

DownStream

  • 2,3-dibroMo-6,7-dichloroquinoxaline
  • 2,3,6,7-TETRACHLOROQUINOXALINE
  • Licostinel

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Novel NMDA/glycine site antagonists attenuate cocaine-induced behavioral toxicity.

Eur. J. Pharmacol. 338 , 233-242, (1997)

N-Methyl-D-aspartate (NMDA)/glycine site antagonists were tested for their ability to prevent cocaine-induced convulsions and lethality in Swiss Webster mice. Pre-treatment of mice with the novel NMDA...

6,7-Dichloroquinoxaline-2,3-dione is a competitive antagonist specific to strychnine-insensitive [3H]glycine binding sites on the N-methyl-D-aspartate receptor complex.

J. Neurochem. 54 , 699-702, (1990)

Multiple binding sites on the N-methyl-D-aspartate (NMDA) receptor complex were examined using rat brain synaptic membranes treated with Triton X-100. Binding of [3H](+)-5-methyl-10,11-dihydro-5H-dibe...


More Articles

Related Compounds

  • 5-nitro-6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione
  • 6,7-dichloro-1,4-dimethyl-quinoxaline-2,3-dione
  • 6,7-diamino-1,4-dihydroquinoxaline-2,3-dione hydrochloride
  • 6,7-dibromoquinoxaline-2,3(1H,4H)-dione
  • 6,7-dimethyl-5-nitro-1,4-dihydroquinoxaline-2,3-dione
  • 6,7-difluoroquinoxaline-2,3(1H,4H)-dione
  • Tert-butyl 3-(5-aminopyridin-3-yl)pyrrolidine-1-carboxylate
  • Tert-butyl 2-(4-amino-1,1-dioxo-1lambda6-thian-4-yl)acetate
  • Tert-butyl 2-(3-amino-1,1-dioxo-1lambda6-thian-3-yl)acetate
  • 3-(2-Bromophenyl)-4,4-difluorobutan-1-amine
  • 3-(3-Bromophenyl)-4,4-difluorobutan-1-amine
  • 3-(4-Bromophenyl)-4,4-difluorobutan-1-amine
  • 7-Bromo-1-methyl-2-naphthalenecarboxylic acid
  • 1-benzyl-5-bromo-1H-pyrazole-4-carbaldehyde
  • 1-(2-Bromophenyl)-5-methylpyrazole-3-carbaldehyde
  • 1-(4-Bromophenyl)-5-methylpyrazole-3-carbaldehyde
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