warfarin-potassium

Names

[ Name ]:
warfarin-potassium

[Synonym ]:
Warfarin-potassium [ISO]
Antrombin K
Athrombin-K
Warfarin K
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one potassium salt
Potassium warfarin
potassium,2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate
monopotassium (RS)-2-oxo-3-(3-oxo-1-phenylbutyl)-chromen-4-olate
rac-potassium 2-oxo-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-4-olate
potassium 2-oxo-3-[(RS)-3-oxo-1-phenylbutyl]-2H-chromen-4-olate
warfarin potassium

Chemical & Physical Properties

[ Density]:
1.307g/cm3

[ Boiling Point ]:
515.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₉H₁₆O₄

[ Molecular Weight ]:
308.32800

[ Flash Point ]:
188.8ºC

[ Exact Mass ]:
308.10500

[ PSA ]:
67.51000

[ LogP ]:
3.60960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4600000

CHEMICAL NAME :: Coumarin, 3-(alpha-acetonylbenzyl)-4-hydroxy-, potassium salt

CAS REGISTRY NUMBER :: 2610-86-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C19-H15-O4.K

MOLECULAR WEIGHT :: 346.44

WISWESSER LINE NOTATION :: T66 BOVJ DYR&1V1 EO &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 58 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 186 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 232 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

Safety Information

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

Warfarin sodium
warfarin sodium
Warfarin
Warfarin
warfarin-deanol
WARFARIN RELATED COMPOUND A (50 MG) (3-(O-HYDROXYPHENYL)-5-PHENYL-2-CYCLOHEXEN-1-ONE)
4-(1-Fluorocyclopropyl)-6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Maleic acid, mono(4-hydroxy-2-butynyl) ester
5-(2,2,3,3-Tetrafluoropropyl)-1,9-dioxa-4-azaspiro[5.5]undecane
5-[1-(1H-1,2,3-triazol-4-yl)cyclopropyl]furan-2-carbaldehyde
4-Cyclopropyl-6-(fluoromethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
4-Cyclopropyl-6-methoxy-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
3-Ethyl-4,5-dihydro-1,5-diphenyl-1H-pyrazole
2-[(Trimethylsilyl)methyl]oxane-2-carbaldehyde
1-(3,3,3-Trifluoro-2-hydroxypropyl)cyclopropane-1-carbaldehyde
1-(2-Hydroxycyclobutyl)cyclopropane-1-carbaldehyde

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