Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI)

Suppliers

Names

[ CAS No. ]:
2618-22-6

[ Name ]:
Glycine,N-formyl-N-hydroxy-, monosodium salt (8CI,9CI)

[Synonym ]:
N-Formylhydroxyaminoessigsaeure-natrium
Hadacidin sodium salt
N-formyl-N-hydroxyglycine Na salt
Hedacidin
Sodium N-hydroxy-N-formylglycinate
Sodium hadacidin
Hadacidin sodium
hadacidine monosodium salt
Hadacidin monosodium salt
Amchem 61-265

Chemical & Physical Properties

[ Density]:
1.592g/cm3

[ Boiling Point ]:
367.1ºC at 760mmHg

[ Molecular Formula ]:
C3H5NNaO4+

[ Molecular Weight ]:
142.06600

[ Flash Point ]:
175.8ºC

[ Exact Mass ]:
142.01200

[ PSA ]:
77.84000

[ Vapour Pressure ]:
7.03E-07mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MC0555000
CHEMICAL NAME :
Glycine, N-formyl-N-hydroxy-, sodium salt
CAS REGISTRY NUMBER :
2618-22-6
LAST UPDATED :
198910
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C3-H4-N-O4.Na
MOLECULAR WEIGHT :
141.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1176 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1764 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1764 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - mouse Embryo
DOSE/DURATION :
4 gm/L/2D
REFERENCE :
ECEBDI Experimental Cell Biology. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.44- 1976- Volume(issue)/page/year: 46,152,1978

Synthetic Route

Precursor & DownStream

Precursor

  • (Hydroxyamino)acetic acid
  • 5-methyl-2-sulfanylidene-1,3,4-thiadiazole-3-carbaldehyde
  • 2-(N-(formyloxy)formamido)acetic acid

DownStream


Related Compounds

  • 1-[3-fluoro-4-(4-methanesulfonyl-1H-pyrazol-1-yl)phenyl]ethan-1-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (1-Fluorocyclopentyl)methanesulfonyl fluoride
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-bromo-N,2,5-trimethylthiophene-3-sulfonamide
  • 1-[1-(3,3-Difluorocyclobutyl)cyclopropyl]ethan-1-ol
  • methyl 2-(3-amino-4-chloro-1H-pyrazol-1-yl)butanoate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-[1-(Hydroxymethyl)-2-methylcyclopropyl]-5,5-dimethyloxolan-3-ol