N-(3-CHLORO-4-FLUOROPHENYL)-7-(3-MORPHOLINOPROPOXY)-6-NITROQUINAZOLIN-4-AMINE

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Names

[ CAS No. ]:
267243-64-1

[ Name ]:
N-(3-CHLORO-4-FLUOROPHENYL)-7-(3-MORPHOLINOPROPOXY)-6-NITROQUINAZOLIN-4-AMINE

[Synonym ]:
(3-chloro-4-fluorophenyl)-[7-(3-morpholino-4-yl-propoxy)-6-nitroquinazolin-4-yl]-amine
(3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitro-quinazoline-4-yl]-amine
I14-9229
(3-CHLORO-4-FLOUROPHENYL)-[7-(3-MORPHOLIN-4-YL-PROPOXY)-6-NITRO-QUINAZOLINE-4YL]-AMINE
N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine
4-[N-(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-nitroquinazoline
(3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitroquinazolin-4-yl]-amine

Chemical & Physical Properties

[ Density]:
1.418g/cm3

[ Boiling Point ]:
637.065ºC at 760 mmHg

[ Molecular Formula ]:
C21H21ClFN5O4

[ Molecular Weight ]:
461.87400

[ Flash Point ]:
339.085ºC

[ Exact Mass ]:
461.12700

[ PSA ]:
105.33000

[ LogP ]:
4.70930

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.649

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine
  • 3-(4-Morpholinyl)-1-propanol
  • 3-Chloro-4-fluoroaniline
  • 7-Fluoro-6-nitro-4-hydroxyquinazoline
  • N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
  • potassium t-butoxide
  • 4-Chloro-7-fluoro-6-nitroquinazoline

DownStream

  • N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine

Related Compounds

  • 1-(2,3-Dimethylphenyl)-4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine
  • 6-[4-(4-Fluorophenyl)piperazin-1-yl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazine
  • 6-[4-(4-Methoxyphenyl)piperazin-1-yl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazine
  • N-(2-chlorobenzyl)[1,2,4]triazolo[4,3-b]pyridazin-6-amine
  • 1-{[1,2,4]Triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carboxamide
  • 6-(4-Phenylpiperazin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine
  • 6-(4-Benzylpiperidin-1-yl)[1,2,4]triazolo[4,3-b]pyridazine
  • N-benzyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine
  • 2-(3-Methyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1,2,3,4-tetrahydroisoquinoline
  • (2S)-N-(3-iodophenyl)pyrrolidine-2-carboxamide
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