4alpha-PDD
Suppliers
Names
[ CAS No. ]:
27536-56-7
[ Name ]:
4alpha-PDD
[Synonym ]:
4a-phorbol 12,13-didecanoate
Phorbol-9,9a-didecanoat
4a-phenyl-4,4a,5,6,7,8-hexahydro-2H-cinnolin-3-one
Chemical & Physical Properties
[ Density]:
1.14g/cm3
[ Boiling Point ]:
734.2ºC at 760mmHg
[ Molecular Formula ]:
C40H64O8
[ Molecular Weight ]:
672.93100
[ Flash Point ]:
212.4ºC
[ Exact Mass ]:
672.46000
[ PSA ]:
130.36000
[ LogP ]:
7.31330
[ Vapour Pressure ]:
6.92E-25mmHg at 25°C
[ Index of Refraction ]:
1.546
[ Storage condition ]:
-20°C
MSDS
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H310 + H330-H334-H351
[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+: Very toxic;
[ Risk Phrases ]:
26/27/28-40-43
[ Safety Phrases ]:
36/37/39-45
[ RIDADR ]:
UN 2811 6.1/PG 2
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Articles
Pflugers Arch. 464(3) , 261-72, (2012)
Pulmonary hypertension, the main disease of the pulmonary circulation, is characterized by an increase in pulmonary vascular resistance, involving proliferation and migration of pulmonary arterial smo...
Am. J. Physiol. Lung Cell. Mol. Physiol. 297(4) , L650-7, (2009)
Pulmonary vascular endothelial cells express a variety of ion channels that mediate Ca(2+) influx in response to diverse environmental stimuli. However, it is not clear whether Ca(2+) influx from disc...
Hypertension 53(2) , 228-35, (2009)
To test the hypothesis that activation of the transient receptor potential vanilloid 4 (TRPV4) channel conveys a hypotensive effect that is enhanced during salt load, male Wistar rats fed a normal-sod...