Rosuvastatin

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Names

[ CAS No. ]:
287714-41-4

[ Name ]:
Rosuvastatin

[Synonym ]:
Reference source: Negwer
volume-3 compound no
ROSUVASTATIN-D3 SODIUM SALT
7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl-d(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, sodium salt, (3R,5S,6E)- (1:1)
[3H]-Rosuvastatin
Rosuvastatin
Sodium (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[(H)methyl(methylsulfonyl)amino]-5-pyrimidinyl}-3,5-dihydroxy-6-heptenoate
(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-MethylMethanesulfonaMido)-6-(propan-2-yl)pyriMidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
MFCD08460959

Chemical & Physical Properties

[ Density]:
1.368 g/cm3

[ Boiling Point ]:
745.6ºC at 760 mmHg

[ Molecular Formula ]:
C22H28FN3O6S

[ Molecular Weight ]:
481.54

[ Flash Point ]:
404.7ºC

[ PSA ]:
152.13000

[ LogP ]:
2.14780

[ Vapour Pressure ]:
2.38E-23mmHg at 25°C

[ Index of Refraction ]:
1.597

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Rosuvastatin methanamine salt
  • 5-Oxorosuvastatin Methyl Ester
  • tert-butyl 2-[6-[(E)-2-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-heptenoic acid iso-propylammonium salt
  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • Rosuvastatin methyl ester
  • tert-Butyl rosuvastatin
  • Rosuvastatin ethyl ester
  • N-[4-(4-Fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide

DownStream

  • Rosuvastatin Lactone

Related Compounds

  • ROSUVASTATIN
  • Rosuvastatin
  • rosuvastatin
  • Rosuvastatin D3
  • Rosuvastatin zinc
  • ROSUVASTATIN Inter
  • 3-(4-Fluoro-2-methylphenyl)propane-1-thiol
  • 2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propan-2-ol
  • {Bicyclo[2.2.2]octan-2-yl}methanesulfonyl fluoride
  • N-(1-Oxido-1l6,3-thiazinan-1-ylidene)acetamide
  • Ethyl 6-bromo-3-(cyanomethyl)benzofuran-2-carboxylate
  • (S)-1-(3-Fluoro-4-(trifluoromethyl)phenyl)but-3-en-1-amine
  • 1-Fluoro-4-[1,1,2,2-tetrafluoro-2-(2-methoxyphenoxy)ethyl]benzene
  • Methyl 3-amino-3-(3-chloro-2-methylphenyl)propanoate
  • (S)-1-(4-Chloro-3-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine
  • 3,3-Dicyclopropyl-2-(ethoxycarbonyl)propanoic acid