Avosentan

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Names

[ CAS No. ]:
290815-26-8

[ Name ]:
Avosentan

[Synonym ]:
Avosentan
UNII-L94KSX715K
2-Pyridinesulfonamide, N-[6-methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-
N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide
Ro 67-0565
SPP301

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
575.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H21N5O5S

[ Molecular Weight ]:
479.508

[ Flash Point ]:
301.8±32.9 °C

[ Exact Mass ]:
479.126343

[ PSA ]:
133.80000

[ LogP ]:
0.87

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Methylpyridine-2-sulfonaMide

DownStream

Related Compounds

  • Avosentan-d3
  • 6-(1-benzofuran-5-yl)-1-phenoxy-1H-pyrrolo[3,2-b]pyridine
  • tert-Butyl 3-[(benzylamino)carbonyl]thien-2-ylcarbamate
  • Toluene-acetic anhydride
  • 4-butoxy-3-(propan-2-yl)-N-[(pyridin-2-yl)methyl]benzene-1-sulfonamide
  • 3-(1-{[(Benzyloxy)carbonyl]amino}cyclopropyl)propanoic acid
  • Ethyl 2-(3-methylbutyl)-1,3-thiazole-4-carboxylate
  • 3-(4-Bromo-phenyl)-6-chloro-1-cyclopropyl-1h-pyrimidine-2,4-dione
  • 2,6-Dichloro-4-(2-(dimethylamino)vinyl)nicotinonitrile
  • 1-(4-bromo-phenyl)-6-chloro-3-cyclopropyl-1H-pyrimidine-2,4-dione
  • Deiodo Trametinib
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