Avosentan

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Names

[ CAS No. ]:
290815-26-8

[ Name ]:
Avosentan

[Synonym ]:
Avosentan
UNII-L94KSX715K
2-Pyridinesulfonamide, N-[6-methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-
N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide
Ro 67-0565
SPP301

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
575.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H21N5O5S

[ Molecular Weight ]:
479.508

[ Flash Point ]:
301.8±32.9 °C

[ Exact Mass ]:
479.126343

[ PSA ]:
133.80000

[ LogP ]:
0.87

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Methylpyridine-2-sulfonaMide

DownStream

Related Compounds

  • Avosentan-d3
  • 1-(1,3-benzothiazol-2-yl)-3-(2-chlorophenyl)-1H-pyrazol-5-ol
  • 1-(1,3-benzothiazol-2-yl)-3-(3-methoxyphenyl)-1H-pyrazol-5-ol
  • 1-(1,3-benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)-1H-pyrazol-5-ol
  • 1-(1H-benzimidazol-2-yl)-3,4-dimethyl-1H-pyrazol-5-ol
  • 1-(1H-benzimidazol-2-yl)-3-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]methyl}-1H-pyrazol-5-ol
  • 1-(1H-benzimidazol-2-yl)-3-methyl-4-pentyl-1H-pyrazol-5-ol
  • 2-(1H-benzimidazol-2-yl)-4,5,6,7-tetrahydro-2H-indazol-3-ol
  • 2-methoxy-N-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)benzamide
  • 3,4,5-trimethoxy-N-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)benzamide
  • N-[3-(4-chlorophenyl)-4-methyl-3H-1,5-benzodiazepin-2-yl]cyclopropanecarboxamide
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