Avosentan

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Names

[ CAS No. ]:
290815-26-8

[ Name ]:
Avosentan

[Synonym ]:
Avosentan
UNII-L94KSX715K
2-Pyridinesulfonamide, N-[6-methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-
N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide
Ro 67-0565
SPP301

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
575.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H21N5O5S

[ Molecular Weight ]:
479.508

[ Flash Point ]:
301.8±32.9 °C

[ Exact Mass ]:
479.126343

[ PSA ]:
133.80000

[ LogP ]:
0.87

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Methylpyridine-2-sulfonaMide

DownStream

Related Compounds

  • Avosentan-d3
  • 1-(cyclobutylmethyl)-4-formyl-1H-pyrazole-5-sulfonyl chloride
  • 2-Cyclopropyl-6-nitro-1,3-benzothiazole-4-thiol
  • 6-Bromo-2-methyl-1,3-benzothiazole-4-thiol
  • (1S)-1-[1-cyclopropyl-3-(2-methylpropyl)-1H-pyrazol-5-yl]ethan-1-amine
  • (1S)-1-(3-cyclobutyl-1-cyclopropyl-1H-pyrazol-5-yl)ethan-1-amine
  • (1S)-1-[1-cyclopropyl-3-(oxolan-3-yl)-1H-pyrazol-5-yl]ethan-1-amine
  • (1S)-1-[1-(cyclobutylmethyl)-3-methyl-1H-pyrazol-5-yl]ethan-1-amine
  • 4-(2,6-Dimethylpiperidin-1-yl)-2-hydroxybenzaldehyde
  • 4-(3,5-Dimethylpiperidin-1-yl)-2-hydroxybenzaldehyde
  • 1-(3-butyl-1-methyl-1H-pyrazol-5-yl)ethan-1-one
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