L-Kynurenine

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Names

[ Name ]:
L-Kynurenine

[Synonym ]:
(S)-α,2-diamino-γ-oxo-Benzenebutanoic acid
(S)-a,2-diamino-g-oxo-Benzenebutanoic acid
3-Anthraniloyl-L-alanine
Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-
L-3-(o-Aminobenzoyl)alanine
3-anthraniloyl-alanine
3-Anthraniloylalanine
Alanine, 3-anthraniloyl-, L-
Kynurenine, L-
L-KYNURENINE
(2S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
(S)-a,2-diamino-γ-oxo-Benzenebutanoic acid
Kynurenine
Benzenebutanoic acid, α,2-diamino-γ-oxo-, (S)-
L-Kynurenin
(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
MFCD00069912
(S)-α,2-Diamino-γ-oxobenzenebutanoic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
466.6±45.0 °C at 760 mmHg

[ Melting Point ]:
302.49° C

[ Molecular Formula ]:
C₁₀H₁₂N₂O₃

[ Molecular Weight ]:
208.214

[ Flash Point ]:
236.0±28.7 °C

[ Exact Mass ]:
208.084793

[ PSA ]:
106.41000

[ LogP ]:
1.09

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.626

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CY9049700

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Kynurenine
(2S)-Methyl 2-(N-tert-butoxycarbonylamino)-4-oxo-4-(2'-aminophenyl)butanoate
L(-)-Tryptophan
2-Iodoaniline

DownStream

Kynurenic acid
L-alanine
Anthranilic acid
2-Amino-3,5-dibromobenzoic acid
3-amino-1-(2-aminophenyl)propan-1-one
2-Quinolinecarboxylicacid,3,4-dihydroxy-(9CI)
3-Hydroxyquinoline-2-carboxylic acid

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats.

Biosci. Biotechnol. Biochem. 79(1) , 103-8, (2015)

The conversion of tryptophan (Trp) → nicotinamide (Nam) is an important pathway for supplying vitamin niacin. We reported the following two phenomena: (1) severe food restriction led to an increase in...

The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.

J. Nutr. Sci. Vitaminol. 60(4) , 261-8, (2014)

The adverse effects of D-tryptophan and the possibility of it being a surrogate index for predicting adverse effects in rats were investigated. Male rats were fed one of several test diets (20% casein...

Organic anion transporting polypeptides 1B1 and 1B3 play an important role in uremic toxin handling and drug-uremic toxin interactions in the liver.

J. Pharm. Pharm. Sci. 17(4) , 475-84, (2015)

Organic anion-transporting polypeptide (OATP) 1B1 and OATP1B3 contribute to hepatic uptake of numerous drugs. Thus, reduced OATP1B1 and OATP1B3 activity in chronic kidney disease (CKD) may have a majo...

L-kynurenine
L-Kynurenine-d4-1
Fmoc-L-Kynurenine
L-KYNURENINE SULFATE
L-Kynurenine Sulfate
l-kynurenine sulfate
tert-butyl N-(1,1,1-trifluorohex-5-en-3-yl)carbamate
rac-(1R,5S)-bicyclo[3.1.0]hexane-2-thiol
2-(3-Amino-4-propyloxolan-3-yl)acetic acid
rac-(1R,2R)-2-(4-chloro-1-ethyl-1H-imidazol-5-yl)cyclopropane-1-carboxylic acid
9-Cyclopropyl-4-methyl-1-oxa-5,9-diazaspiro[5.5]undecane
1-[2-(3-Ethyloxetan-3-yl)propan-2-yl]cyclopropan-1-amine
[1-(4-Ethylcyclohexyl)-2,2-difluorocyclopropyl]methanamine
1-(3-Ethyloxetan-3-yl)ethane-1,2-diol
3-Amino-3-(1,1-dioxo-1lambda6-thietan-3-yl)butanoic acid
5-Bromo-2,3-dihydro-4-[[2-(trimethylsilyl)ethoxy]methoxy]benzofuran

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