Licarbazepine

Suppliers

Names

[ Name ]:
Licarbazepine

[Synonym ]:
10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,Licarbazepine
Licarbazepine,10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide
10,11-Dihydro-10-hydroxy Carbamazepine
10,11-Dihydro-10-hydroxycarbamazepine
5H-Dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-

Chemical & Physical Properties

[ Density]:
1.336g/cm3

[ Boiling Point ]:
431.3ºC at 760mmHg

[ Melting Point ]:
186-189ºC

[ Molecular Formula ]:
C₁₅H₁₄N₂O₂

[ Molecular Weight ]:
254.28400

[ Flash Point ]:
214.6ºC

[ Exact Mass ]:
254.10600

[ PSA ]:
66.56000

[ LogP ]:
3.25820

[ Vapour Pressure ]:
3.33E-08mmHg at 25°C

[ Index of Refraction ]:
1.677

[ Storage condition ]:
Store at RT

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H332-H319

[ Precautionary Statements ]:
P210-P305 + P351 + P338

[ Hazard Codes ]:
N,Xn,F

[ Risk Phrases ]:
51/53-36-20/21/22-11

[ Safety Phrases ]:
61-36/37-26-16

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

carbamazepine-10,11-epoxide
10-chloro-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide
Oxcarbazepine
5-Carbamoyl-5H-dibenz[b,f]azepinEN5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine
Carbamazepine
10,11-Dihydrocarbamazepine

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

First MEPS/HPLC assay for the simultaneous determination of venlafaxine and O-desmethylvenlafaxine in human plasma.

Bioanalysis 6(22) , 3025-38, (2014)

A new high-performance liquid chromatography-fluorescence detection assay based on microextraction by packed sorbent as sample preparation approach is described to quantify venlafaxine (VEN) and its m...

Evaluation of the matrix effect of different sample matrices for 33 pharmaceuticals by post-column infusion.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1000 , 84-94, (2015)

Matrix effects that occur during quantitative measurement by liquid chromatography mass spectrometry specifically when using electrospray ionization are a widely recognized phenomenon. Sample matrix c...