Nicotredole
Suppliers
Names
[ CAS No. ]:
29876-14-0
[ Name ]:
Nicotredole
[Synonym ]:
nicotredole
3-Pyridinecarboxamide, N-[2-(1H-indol-3-yl)ethyl]-
Tryptamide
N-Nicotinoyltryptamide
N-[2-(1H-Indol-3-yl)ethyl]nicotinamide
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
588.4±35.0 °C at 760 mmHg
[ Molecular Formula ]:
C16H15N3O
[ Molecular Weight ]:
265.310
[ Flash Point ]:
309.7±25.9 °C
[ Exact Mass ]:
265.121521
[ PSA ]:
57.78000
[ LogP ]:
1.94
[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C
[ Index of Refraction ]:
1.669
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QS4476800
- CHEMICAL NAME :
- Nicotinamide, N-(2-indol-3-ylethyl)-
- CAS REGISTRY NUMBER :
- 29876-14-0
- BEILSTEIN REFERENCE NO. :
- 0242441
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H15-N3-O
- MOLECULAR WEIGHT :
- 265.34
- WISWESSER LINE NOTATION :
- T56 BMJ D2MV- CT6NJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,313,1970 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 90 mg/kg
- SEX/DURATION :
- female 6-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 39,779,1987
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4500 mg/kg
- SEX/DURATION :
- female 6-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 39,779,1987
Safety Information
[ Hazard Codes ]:
Xi