C2-8

Names

[ Name ]:
C2-8

[Synonym ]:
N-(4-bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide
C2-8
Polyglutamine Aggregation Inhibitor III,C2-8

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₄Br₂N₂O₃S

[ Molecular Weight ]:
510.19900

[ Exact Mass ]:
507.90900

[ PSA ]:
83.65000

[ LogP ]:
6.49150

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H413

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.

Proc. Natl. Acad. Sci. U. S. A. 102 , 892-897, (2005)

Polyglutamine (polyQ) disorders, including Huntington's disease (HD), are caused by expansion of polyQ-encoding repeats within otherwise unrelated gene products. In polyQ diseases, the pathology and d...

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4-(3-bromo-1-methyl-1H-pyrazol-5-yl)but-3-en-2-one
2-[(E)-2-cyclohexylprop-1-enyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1-(4-Bromophenyl)-3,3-dimethylcyclopentan-1-ol
(5-Chloro-4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetic acid methyl ester
5-Chloro-1,6-dihydro-4-(4-morpholinyl)-6-oxo-2-pyrimidineacetic acid
(5-Chloro-4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetic acid ethyl ester
6-(morpholin-4-yl)-2-[2-oxo-2-(4-phenyl-2,3-dihydro-1H-indol-1-yl)ethyl]pyrimidin-4(3H)-one

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