C2-8

Modify Date: 2024-01-16 18:47:47

C2-8 structure	Common Name	C2-8
	CAS Number	300670-16-0	Molecular Weight	510.19900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₄Br₂N₂O₃S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of C2-8

A small molecule inhibitor of polyglutamine (polyQ) aggregation in Huntington's disease neurons.

Name	N-(4-bromophenyl)-3-[(4-bromophenyl)sulfamoyl]benzamide
Synonym	More Synonyms

Molecular Formula	C₁₉H₁₄Br₂N₂O₃S
Molecular Weight	510.19900
Exact Mass	507.90900
PSA	83.65000
LogP	6.49150

C2-8 MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319-H413
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
RIDADR	NONH for all modes of transport
HS Code	2935009090

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.

Proc. Natl. Acad. Sci. U. S. A. 102 , 892-897, (2005)

Polyglutamine (polyQ) disorders, including Huntington's disease (HD), are caused by expansion of polyQ-encoding repeats within otherwise unrelated gene products. In polyQ diseases, the pathology and d...

N-(4-bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide

C2-8

Polyglutamine Aggregation Inhibitor III,C2-8