1-(3,5-Bis(trifluoromethyl)phenyl)ethanone

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Names

[ CAS No. ]:
30071-93-3

[ Name ]:
1-(3,5-Bis(trifluoromethyl)phenyl)ethanone

[Synonym ]:
EINECS 250-023-7
Ethanone, 1-[3,5-bis(trifluoromethyl)phenyl]-
3,5-Bis(Trifluoromethyl)Acetophenone
1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-one
1-Acetyl-3,5-bis(trifluoromethyl)benzene
MFCD00009910
1-[3,5-Bis(trifluoromethyl)phenyl]ethanone
3′,5′-Bis(trifluoromethyl)acetophenone
FXFFR CV1 EXFFF
3’,5’-Bis(trifluoromethyl)acetophenone
3,5-ditrifluoromethylacetophenone
1-(3,5-Bis(trifluoromethyl)phenyl)ethanone
3',5'-Bis(trifluoromethyl)acetophenone
MBT-AC

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
162.7±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H6F6O

[ Molecular Weight ]:
256.145

[ Flash Point ]:
82.2±0.0 °C

[ Exact Mass ]:
256.032288

[ PSA ]:
17.07000

[ LogP ]:
4.06

[ Vapour Pressure ]:
2.1±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.407

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S37/39

[ RIDADR ]:
3439

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,5-Bis(trifluoromethyl)bromobenzene
  • 3,5-bis-trifluoromethyl-benzoyl fluoride
  • Tetramethyltin
  • (R)-1-[3,5-bis(trifluoromethyl)-phenyl]ethan-1-ol
  • Ethanoic anhydride
  • Acetyl chloride
  • 1,3-Bis(trifluoromethyl)benzene
  • 3,5-Bis(trifluoromethyl)benzoic acid
  • METHYLLITHIUM
  • 3,5-Bis(trifluoromethyl)benzoyl chloride

DownStream

  • (S)-N-Methyl-1-[3,5-bis(trifluoromethyl)phenyl]ethylamine
  • (R)-N-Methyl-1-[3,5-bis(trifluoromethyl)phenyl]ethylamine
  • 3,5-Bis(trifluoromethyl)phenol
  • (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
  • (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
  • (2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)morpholine
  • 4-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)THIAZOL-2-AMINE
  • 2-[3,5-bis-(Trifluoromethyl)phenyl]propan-2-ol
  • 1-[3,5-bis(trifluoromethyl)phenyl]-3-(dimethylamino)prop-2-en-1-one
  • (2R)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]morpholin-3-one

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs.

J. Med. Chem. 38 , 3874-83, (1995)

A large series (66 compounds) of indeno[1,2-c]pyridazin-5-ones (IPs) were synthesized and tested on their monoamine oxidase-A (MAO-A) and MAO-B inhibitory activity. All of the tested compounds acted p...

Asymmetric biocatalytic reduction of 3,5-bis(trifluoromethyl) acetophenone to (1R)-[3,5-bis(trifluoromethyl)phenyl] ethanol using whole cells of newly isolated Leifsonia xyli HS0904.

Appl. Microbiol. Biotechnol. 90(6) , 1897-904, (2011)

A novel bacterial strain HS0904 was isolated from a soil sample using 3,5-bis(trifluoromethyl) acetophenone as the sole carbon source. This bacterial isolate can asymmetrically reduce 3,5-bis(trifluor...

Rhodium-catalyzed heterogeneous enantioselective hydrogenation of 3, 5-di-(trifluoromethyl)-acetophenone. Hess R, et al.

J. Mol. Catal. A: Chem. 212(1) , 205-9, (2004)


More Articles

Related Compounds

  • (E)-1-[3,5-bis(trifluoromethyl)phenyl]ethanone O-benzyloxime
  • 1-[3,5-bis(trifluoromethyl)phenyl]-2-(2,6-dimethylphenyl)ethanone
  • 1-((3,5-Bis(trifluoromethyl)phenyl)sulfonyl)piperazine hydrochloride
  • 1-[3,5-bis(trifluoromethyl)phenyl]-2,5-dimethyl-1H-pyrrole
  • 1-[3,5-bis(trifluoromethyl)phenyl]-3-(3,4-dimethoxyphenyl)urea
  • 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-(cyclohexylamino)-1,2-diphenylethyl)thiourea