1-(3,5-Bis(trifluoromethyl)phenyl)ethanone

1-(3,5-Bis(trifluoromethyl)phenyl)ethanone Structure
1-(3,5-Bis(trifluoromethyl)phenyl)ethanone structure
Common Name 1-(3,5-Bis(trifluoromethyl)phenyl)ethanone
CAS Number 30071-93-3 Molecular Weight 256.145
Density 1.4±0.1 g/cm3 Boiling Point 162.7±35.0 °C at 760 mmHg
Molecular Formula C10H6F6O Melting Point N/A
MSDS Chinese USA Flash Point 82.2±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs.

J. Med. Chem. 38 , 3874-83, (1995)

A large series (66 compounds) of indeno[1,2-c]pyridazin-5-ones (IPs) were synthesized and tested on their monoamine oxidase-A (MAO-A) and MAO-B inhibitory activity. All of the tested compounds acted preferentially on MAO-B displaying weak (nonmeasurable IC50 ...

Asymmetric biocatalytic reduction of 3,5-bis(trifluoromethyl) acetophenone to (1R)-[3,5-bis(trifluoromethyl)phenyl] ethanol using whole cells of newly isolated Leifsonia xyli HS0904.

Appl. Microbiol. Biotechnol. 90(6) , 1897-904, (2011)

A novel bacterial strain HS0904 was isolated from a soil sample using 3,5-bis(trifluoromethyl) acetophenone as the sole carbon source. This bacterial isolate can asymmetrically reduce 3,5-bis(trifluoromethyl) acetophenone to (1R)-[3,5-bis(trifluoromethyl)phen...

Rhodium-catalyzed heterogeneous enantioselective hydrogenation of 3, 5-di-(trifluoromethyl)-acetophenone. Hess R, et al.

J. Mol. Catal. A: Chem. 212(1) , 205-9, (2004)